Parkinson's Disease Tulip


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Old 02-20-2014, 09:28 AM #61
zanpar321 zanpar321 is offline
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Quote:
Originally Posted by zanpar321 View Post
It's the SNP location rs1801133. The 1298 mutation also needs to be checked rs1801131.

See mine below

Gene

MTHFR C677T rs1801133 AG +/- (if you have two +'s then you metabolize at 30%)
MTHFR 1298 rs1801131 TT -/- (so I don't have this mutation).

You can get a free analysis of 23andme data at geneticgenie.org. Another great resource is

http://mthfr.net/

I hope this helps.
Good morning Badboy,

Were you able to find your 677 dna data?
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Old 02-20-2014, 11:31 AM #62
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Got it +/+

So that means 40% of normal?
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Originally Posted by zanpar321 View Post
Good morning Badboy,

Were you able to find your 677 dna data?
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Old 02-20-2014, 11:43 AM #63
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Hmm . . . this is very interesting about the coconut oil . . . I will need to pass along the info to my FIL as he has parkinsons.
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Old 02-20-2014, 12:00 PM #64
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Quote:
Originally Posted by badboy99 View Post
Got it +/+

So that means 40% of normal?
Regarding the percent, see the link below. It may seem like not the best news but at least now you have a starting point to fix it and on your way to start making more glutathione/dopamine. Be sure to check the 1298 gene too. Alot of folks apparently have one or both of these variations. This is exciting data and I believe will be of tremendous use in treating PD and many other ailments! I'm not a doc, but the link below does a great job to explain this. Suggest you listen to both videos from Dr Smith. I am looking for a doc that is DNA literate but haven't found one yet so am just trying to learn what I can to improve my health. I started taking 5-MTHF and methyl B12. Will let you know how things go. Best regards!

http://www.youtube.com/watch?v=tBUCe...FB6636&index=5

Another great website to analyze DNA data for free is shown below:


www.knowyourgenetics.com

Last edited by zanpar321; 02-20-2014 at 01:06 PM.
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Old 02-20-2014, 04:01 PM #65
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Badboy - attached is the Keto diet plan...


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Originally Posted by badboy99 View Post
anagirl, Thanks for your post. I am interested in trying out your diet since I'm low carb/sugar already. Would you mind posting it. Thank you.
Attached Files
File Type: pdf RC Diet.pdf (123.2 KB, 167 views)
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Old 02-20-2014, 04:04 PM #66
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Originally Posted by zanpar321 View Post
Good morning Badboy,

Were you able to find your 677 dna data?

i was looking for mine too - but unable to find it. perhaps i need to update my 23andme profile. :-(
i'll keep trying - this is super interesting info!
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Old 02-20-2014, 06:46 PM #67
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Quote:
Originally Posted by anagirl View Post
i was looking for mine too - but unable to find it. perhaps i need to update my 23andme profile. :-(
i'll keep trying - this is super interesting info!
You can find it by entering Ctrl - F and searching for rs1801133 in the data.
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Old 02-20-2014, 08:25 PM #68
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Quote:
Originally Posted by anagirl View Post
i was looking for mine too - but unable to find it. perhaps i need to update my 23andme profile. :-(
i'll keep trying - this is super interesting info!
Ana, I've posted this several times in the past, but it's definitely worth repeating again:

For those who have downloaded their 23andMe raw data, I highly recommend viewing all articles and databases with a Firefox browser and the SNPTips add-on. This will show your personal genotype results on the page for whatever SNP location is mentioned in the article or research study (assuming it was measured by 23andme). This makes it dramatically easier to see your genetic results whenever you read something that references a SNP. For example, when Zanpar writes about the two MTHFR SNPs of interest to this thread, when I view his post, the SNPs are highlighted in green and, if 23andMe has tested for this location, it will show my personal results. No database opening, no searching, no ctrl-f, etc. Its a wonderful tool when you are reading genetic studies.

Last edited by Tupelo3; 02-20-2014 at 10:00 PM.
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Old 02-20-2014, 08:38 PM #69
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Default OT - but interesting

This is pretty much off topic, and I have posted it in the past. But some of our new comers may find interest in the sites that I linked.

Since we have had so much discussion recently on this board about genes, mutations, genetic testing, etc., I thought I would share two very valuable databases that I use. They provide great information about specific genes along with links to worldwide research studies:

http://www.thepi.org/parkinson-s-dis...tion-database/
this links to the following data base:
http://grenada.lumc.nl/LOVD2/TPI/hom...tion=switch_db

http://www.pdgene.org/
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Old 02-21-2014, 10:29 PM #70
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so mine says AG orientation minus

any chance you know what this means?


MTHFR 11856378 rs1801133 A or G
AG
Reference Links:
Entrez Gene
Google Scholar (Gene)
dbSNP Lookup
Google Scholar (SNP) dbSNP Orientation: Minus
dbSNP Genotype: CT


Quote:
Originally Posted by zanpar321 View Post
You can find it by entering Ctrl - F and searching for rs1801133 in the data.
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