[michael7733]

Most of us have not reached the age of retirement yet, and we are dependent upon one or more forms of disability income, There are literally millions of us across the globe who fit into this category. Ha ve you ever asked yourself what you will do for income when a cure is found? We will probably be asked to give up our disability incomes and rejoin the workforce. I know that most of yu do not believe that a cure will come in your lifetime, and you could be right...or...you could be wrong.
Five days ago I added a supplement to my daily regimen of Sinemet and Requip. On day one, June 29, 2012, I took 2 capsules of Mega Hydrate. I think I had a little more energy that day, but it didn't seem t o be a significant amount. On day 2 I forgot to take them. I remembered on days 3, 4 and 5. Today is July 3rd, 2012, day 5. I have divided my medication into 5 doses during the day, and I usually get 2 to 3 hours of "ON" time from each dose. I usually go "OFF" about an hour to an hour and a half before my next dose is due. There is a 9 hour space of time between my last dose of the day and the first dose of the next day. During my "OFF" times, I am pretty much dependent on my motorized scooter to get around. Shuffling, rigidity and freezing are in control during those times. As of right now, 2:40 PM, July 3rd, 2012, I have been "ON" for 29 straight hours with no rigidity, no freezing and no shuffling. I consider this to be significant.
I am not saying that this is a cure or even a new area to look in for a treatment. I am not even saying that this supplement caused this to happen. I am say ing that , to me, this is significant.
michael

I am so blessed

[lurkingforacure]

Originally Posted by michael7733

Most of us have not reached the age of retirement yet, and we are dependent upon one or more forms of disability income, There are literally millions of us across the globe who fit into this category. Ha ve you ever asked yourself what you will do for income when a cure is found? We will probably be asked to give up our disability incomes and rejoin the workforce. I know that most of yu do not believe that a cure will come in your lifetime, and you could be right...or...you could be wrong.
Five days ago I added a supplement to my daily regimen of Sinemet and Requip. On day one, July 29, 2012, I took 2 capsules of Mega Hydrate. I think I had a little more energy that day, but it didn't seem t o be a significant amount. On day 2 I forgot to take them. I remembered on days 3, 4 and 5. Today is July 3rd, 2012, day 5. I have divided my medication into 5 doses during the day, and I usually get 2 to 3 hours of "ON" time from each dose. I usually go "OFF" about an hour to an hour and a half before my next dose is due. There is a 9 hour space of time between my last dose of the day and the first dose of the next day. During my "OFF" times, I am pretty much dependent on my motorized scooter to get around. Shuffling, rigidity and freezing are in control during those times. As of right now, 2:40 PM, July 3rd, 2012, I have been "ON" for 29 straight hours with no rigidity, no freezing and no shuffling. I consider this to be significant.
I am not saying that this is a cure or even a new area to look in for a treatment. I am not even saying that this supplement caused this to happen. I am say ing that , to me, this is significant.
michael

I am so blessed

\

I assume you are still taking your meds like you were before you started taking this? If not, how have you changed youre regiment?

[michael7733]

Yes, I am still taking the same meds. The only change I have made is the addition of Mega Hydrate. When I awoke this morning I was still "ON". At this point in time I have had 47 continual hours with no Parkinson's symptoms. Let me say this again. I am not saying that Mega Hydrate is responsible for this. It is just the only change I have made. I supppose the next step would be to see if I can reduce my meds any.

michael

[michael7733]

You are so right, but go toward the beginning of the cascade of events tothe uncoupling of t he oxidative phosphorylation process.Two documents were released by the U.S. government in 2009. The first one stated that Agent Orange uncoupled the oxida tive phosphorylation process, while the other one stated that the uncoupling of the oxidative phosphorylaion process causes Parkinson's disease. Take a look at what happens here. This is where a hydrogen electron is used to create ATP (energy) . Water is a by-product and is used to keep the cell hydrated. This all happens in the Mitochondria. If it doesn't happen the cell begins to dehydrate and the loss of energy triggers a change in the apoptotic time table forcing the cell into an early death. Transport across the cell membrane becomes impossible . Hyperpolarization occurs at the voltage-gated ion channels and they no longer open to release dopamine.

NOW...A BIG WHAT IF...What if the Mega Hydrate was able to make the hydrogen electrons available again? What might we expect to happen? I chose this product hoping for certain results. I was experiencing similar results in the year 2000 with a product called Microhydrin from A company called Royal Body Care, but I had a heat stroke on July 10th of that year that nearly killed me. I have been formulating this theory for 12 years here, but again, I am not saying that this is a cure or even a treatment. What I am saying is that this is significant to me.

michael

[reverett123]

Something similar is going on with creatine. It draws water into the cell, thus rehydrating it. But athletes have to be very careful about dehydrating since less water is circulating. However, for me at least, the dose needed is much lower than called for. About 1/2 tsp instead of 2 to 3 tsp. Too much knocks me out. Oddly enough, magnesium has a similar effect. Ideas?

[Muireann]

The rehydration theory in relation to PD has been proposed elsewhere, with positive results. John Coleman in Australia credits his recovery, in part, to a homeopathic rehydration therapy that was originally devised for athletes, called The Aquas. See http://www.aquas4life.com/

See John's own site http://www.returntostillness.com.au/home.php

He also pays a lot of attention to diet and meditation.

I personally know someone using the Aquas who is doing quite well though he is not rid of the disease. In any case, plenty of water intake is good for the body, and brains especially like to stay spongy.

[moondaughter]

Originally Posted by reverett123

Something similar is going on with creatine. It draws water into the cell, thus rehydrating it. But athletes have to be very careful about dehydrating since less water is circulating. However, for me at least, the dose needed is much lower than called for. About 1/2 tsp instead of 2 to 3 tsp. Too much knocks me out. Oddly enough, magnesium has a similar effect. Ideas?

I noticed longer "on" times with drinking rain water....am considering trying an experiment with distilled water.
Rick have you considered coconut water?? - chock full of bioavailable potassium, magnesium and calcium.

md

[Conductor71]

Originally Posted by michael7733

You are so right, but go toward the beginning of the cascade of events tothe uncoupling of t he oxidative phosphorylation process.Two documents were released by the U.S. government in 2009. The first one stated that Agent Orange uncoupled the oxidative phosphorylation process, while the other one stated that the uncoupling of the oxidative phosphorylaion process causes Parkinson's disease. Take a look at what happens here. This is where a hydrogen electron is used to create ATP (energy) .
michael

Not sure if this relates to what you and Rick are discussing but is interesting in that it supports what you are saying about Hydrogen and Mitochondrial dysfunction. It looks like Hydrogen may just be neuroprotective after all.


Hydrogen in Drinking Water Reduces Dopaminergic Neuronal Loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Mouse Model of Parkinson's Disease.

As for the supplement, could it be both a digestive neutralizer improving both the absorption of and thus metabolism of your meds? Maybe that is a given.

Good for you on the results! That sense of normalcy is a rare bird in PD.

Laura

[michael7733]

That is the first time I have seen that in print outside of what I Have written. YEEEEHAAAAA

michael

[reverett123]

1. Antioxid Redox Signal. 2011 Jul 15;15(2):343-52. Epub 2011 Apr 5.

Inhaled hydrogen sulfide prevents neurodegeneration and movement disorder in a
mouse model of Parkinson's disease.

Kida K, Yamada M, Tokuda K, Marutani E, Kakinohana M, Kaneki M, Ichinose F.

Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General
Hospital, Harvard Medical School, Boston, Massachusetts, USA.

Parkinson's disease is one of the major neurodegenerative disorders. Neurotoxin
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) can cause Parkinson's
disease-like symptoms and biochemical changes in humans and animals. Hydrogen
sulfide (H(2)S) has been shown to protect neurons. The goal of this study was to
examine the effects of inhaled H(2)S in a mouse model of Parkinson's disease
induced by MPTP. Male C57BL/6J mice received MPTP at 80 mg/kg and breathed air
with or without 40 ppm H(2)S for 8 h/day for 7 days. Administration of MPTP
induced movement disorder and decreased tyrosine hydroxylase (TH)-containing
neurons in the substantia nigra and striatum in mice that breathed air.
Inhalation of H(2)S prevented the MPTP-induced movement disorder and the
degeneration of TH-containing neurons. Inhaled H(2)S also prevented apoptosis of
the TH-containing neurons and gliosis in nigrostriatal region after
administration of MPTP. The neuroprotective effect of inhaled H(2)S after MPTP
administration was associated with upregulation of genes encoding antioxidant
proteins, including heme oxygenase-1 and glutamate-cysteine ligase. These
observations suggest that inhaled H(2)S prevents neurodegeneration in a mouse
model of Parkinson's disease induced by MPTP, potentially via upregulation of
antioxidant defense mechanisms and inhibition of inflammation and apoptosis in
the brain.

PMCID: PMC3118610 [Available on 2012/7/15]
PMID: 21050138 [PubMed - indexed for MEDLINE]