There are a lot of doctors peddling nonsense to parents of Autistic children, which the Cutler protocol is aimed at. There is zero evidence that autism is improved by chelation.

The problem with his protocol, one aimed at neuropathology, is that the chelators he uses don't penetrate the brain (they're effectively blocked by the blood brain barrier) and at least after a few months post exposure cessation they don't seem to be of much value.

I do appreciate any help and the goodwill behind any suggestion, but I bear special antipathy for those who peddle false, pseudoscientific hope to parents who have no real hope- and the ridiculous fees they're charging those parents for what are actually very cheap medications. Not to mention that chelators are very real drugs and can have profound consequences on the body and giving them to children when there's no proof of benefit is abhorrent.

I have found one study which found a decrease in brain manganese levels after administration of these typical chelators, but the bulk say no benefit.

GerryW- The Para-amino-SA looks extremely interesting, I wasn't referring to your post when I responded. I have a lot of hope for this- maybe this doesn't have to get worse and worse and worse.


I was hoping to find someone who had been affected by manganese poisoning. Unfortunately the only people I've seen were diagnosed by nutritionists based on ineffective hair tests and showed the usual vague symptoms associated with, well, everything.

I can see why this is so rarely diagnosed, it seems that urine and blood tests are ineffective, there aren't well established blood levels at which symptoms begin, if your exposure to the metal ended more than a month before the test, the reliability is very low. The only well established method of determining whether manganese is causing damage is T1 weighted MRI looking for a hotspot in the globus pallidus.

Considering that inhaling water vapor in your shower of high-manganese water could be enough to cause parkinsonian syndrome after a lifetime of exposure, it's easy to see why manganism is probably underdiagnosed.

If 4-amino-SA is really that effective, it would be interesting to see it's success rate in early onset (or simply early-diagnosis) IPD. If it were able to cure even 5% of newly diagnosed patients, that would likely be worth it (depending on the drugs risks, I'm not sure how safe it is).

Alpha lipoic acid passes the blood brain barrier but best of luck. i tried the cutler protocol 11 years ago right after my diagnosis,my pd symptoms worsened after having a broken amalgem removed so investigated mercury toxicity, had nothing to lose. the cost was the cheap chelators, needed a RX for one of them, and his book, no healthcare individual involved except my neuro wrote me a RX. just recommending a chelation technique that you can do yourself.

1- For your muscle tightness:

Recognize that high doses of any of the following minerals: Iron, Zinc Managanese, or Selenium will lead to a depletion of Vitamin E from the body as the metals enter into biochemical reactions and vit-e is a cofactor. This isn't theoretical...it happened to me and I'm a Natural Medicine doctor.

However, Vitamin E is a muscle tissue lubricant, allowing the muscle fibers to slide across each other during contraction and extension. You lost your lubricant. Easy, just purchase a good vitamin E , best types are the water soluble ones so you can insure correct absorption, but if you have excellent digestion, then just take what are called: Natural Mixed Tocopherals and you will be fine. Take 2500 IU for one month daily then drop down to 1000 IU. Take immediatly after meals, split into twice daily.

2- For Your Neuorological system: The human body is repairable, don't worry. You are correct that the blood brain barrier is hard to cross, but Manganese is not only polluting your brain; its also polluting your nervous system outside the brain. What to do: Introduce powerfull solvents into the body through using safe natural enzymes that are not harmful. Take fresh Ginger Root and using a juicing machine, produce 8 oz daily of pure juice...its very hot to drink but perfectly safe. Drink half of this in morning, and half after six hours. Its tough for the first week to drink, but don't wimp out on us..... This will flush toxins and some heavy metals [ through binding] from your body and it actually crosses the blood brain barrier. After three weeks, drink 8 ounce moring and 8 oz in afternoon.

3- Perform fasting for two days weekly, wheer no food or drink is taken from waking in morning until sundown, Fasting jumpstarts the detoxification cycle of the body. Take a lot of natural juices after sundown, eat two medium size healthy meals, and exercise lightly at night during the fasting period. Continue for two months.

4-Go to a top massage therapist in your city and request a 30 minute deep tissue massage folllowed by a 30 minute Lymphatic massage. Repeat twice weeekly for 2 months. The massage is needed to remove managnese from your tissues. Dring one quart of fresh grapefruit juice before the massage by 30 minutes. The juice will help move fluids out of you, and these fluids clean you out.

5- Try the well known Scientology detoxification....just try it before you judge anything! You can search the procedure on the internet, its a Sauna detox method using sweating.

Good luck Hamilton,

Abdulrahman

.. http://en.wikipedia.org/wiki/Manganism
. It 's a very long researched and complex subject, but it has been proven that certain transition metals exposure in excess leads to neurological problems,, but the whole area is still as clear as muddy water. Full of speculation, postulation. The trouble with chelation therapy is not only BBB penetration and ultimate excretion of the offending agent, whether it be copper, iron, manganese or any transition metal ion, but that the chelator may not be specific at "bonding" to manganese 2+ or 3+ ions , and so will remove any ion within a range of atomic size and charge, that includes certain charged metal ions that are necessary for cellular function.
it sure sounds like you have "manganese induced parkinsonism. I worked as a welder for 7 months when i was young, but i wouldn't say, couldn't say that was responsible for developing PD, 20 years later. Unfortunately they lump you under "idiopathic parkinsonism", of no known cause.