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05-12-2007, 08:42 AM
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ex-Member
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Somebody will usually get milder Parkinson's Disease if their dopamine formation is persistently down to less than 25%. In severe cases the dopamine levels can drop below 10%.
The average person without Parkinson's Disease does not have high levels of dopamine. I doubt if the average person is above 50%. There must also be tens or hundreds of millions of people that are borderline, with dopamine levels of 30% to 40%. In the Rotterdam study, over 6000 people without Parkinson's Disease were assessed for Parkinson's Disease symptoms. Large numbers of them reported Parkinson's Disease symptoms (stiffness, tremors, and imbalance). So these people's dopamine levels must have temporarily been going below the 25% level, but not persistently enough in order to be diagnosed as having Parkinson's Disease. Many never went on to develop Parkinson's Disease. It was a transient problem for them. The formation of dopamine is dependent upon the activity of the enzymes involved in dopamine formation. Enzymes are substances that the body produces that enable chemical reactions to take place in the body. The activity of all enzymes is changing continuously according to need and capability. So nobody, not even somebody known to have Parkinson's Disease, will be producing the same amount of dopamine all the time. Levels can go down, but they can also go up. |
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