I have a somewhat unique position that relates to your concerns. Im a 42 year old male who was diagnosed almost 3 years ago. I have been taking sinemet for about 2 1/2 years. I definitely get relief from the symptoms that you a speaking of. About 2 months ago my mom was diagnosed with pd. I am convinced she has probably had it for about 10 to 12 years. I didn't know anything about pd until I was diagnosed. But knowing what I know now my mom should have been on medication ten years ago. Shes on pd meds now but I thinks its to late, she is totally bedridden, can hardly swallow, and is near the end of a struggle that has progressed for many years. I always wonder if I had known about pd 10 years ago, how much better my moms life would have been. Don't wait any longer get him on meds, that's just my opinion