Parkinson's Disease Tulip


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Old 04-10-2014, 05:36 PM #1
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Default Exenatide possibly neuroprotective

http://www.ncbi.nlm.nih.gov/pubmed/24662192
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Old 04-10-2014, 06:08 PM #2
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Very interesting. Also, once again showing some type of relationship between PD and type 2 diabetes.
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Old 04-12-2014, 07:47 PM #3
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Default byetta-Exenatide

This drug has been around for awhile--just not well studied or utilized in PD. I think there were major problems with pancreatitis with its use in diabetes. Thus it never gained much traction.
a couple of older postings about it:

http://neurotalk.psychcentral.com/sh...ghlight=byetta

and a post by MrsD:
http://neurotalk.psychcentral.com/sh...ghlight=byetta

You can read more about Byetta here:

http://www.byetta.com/index.jsp

It is not popular however, not making it well in the common sector or in nursing homes.

I think this is connected to type III diabetes...that is the BRAIN makes insulin and there must be a connection to PD when this fails.

You know there were posts on inositol...at one time on this forum or at OBT, I can't recall which...because inositol improves glucose utilization in the brain.
I wonder if that is related here? There are mixed opinions on this however..but insulin resistance does respond to inositol use. (diabetics lose this nutrient normally in the urine for some reason-- so need supplements of it).
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Old 04-12-2014, 07:48 PM #4
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Default inositol

anyone using inositol? thanks, madelyn
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Old 04-13-2014, 01:55 AM #5
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Default Pancreatitis risk using BYETTA estimated at 6 in 1000

Quote:
Originally Posted by olsen View Post
This drug has been around for awhile--just not well studied or utilized in PD. I think there were major problems with pancreatitis with its use in diabetes.
Here is a recent article that estimates pancreatitus risk for Byetta. The risk is calculated for diabetics which are prone to pancreatitus.


http://www.bloomberg.com/news/2013-0...itis-risk.html

As olsen correctly points out, Byetta use in PD is still unstudied.
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