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The enzyme asparagine endopeptidase (AEP) mediates pathologic activity in PD & AD

 
 
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Old 07-20-2017, 08:02 AM #2
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kiwi33 kiwi33 is offline
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Thanks jeffreyn.

I know about AEP as its δ-secretase synonym in the context of AD but it would never have occurred to me that it might cleave α-synuclein as well.

Though there is much more work to do, this could be a big step forward in treatment of both AD and PD, especially as candidate inhibitors of AED have been found.
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jeffreyn (07-20-2017), olsen (07-21-2017)
 

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aep, alpha-synuclein, asparagine, chunk, samples

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