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03-07-2018, 06:50 AM | #1 | ||
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Some Parkinson’s Patients May Benefit from Non-dopaminergic Treatments
Parkinson's Patients May Benefit from Non-dopaminergic Treatments |
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03-07-2018, 02:38 PM | #2 | ||
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Similar conclusions were quoted in a recent thread:
Widening the scope and the extent of PD therapy 'Qamar et al. write ...: "Besides dopamine (DA), three further key neurotransmitters have been described to be involved in the pathogenesis of PD; namely noradrenaline (NA), acetylcholine (ACh), and serotonin (5HT)."' It doesn't seem unreasonable to think of Parkinson's as a neurotransmitter disease, rather than just a lack of dopamine disease. Moreover, the standard dopamine replacement therapy is throwing exogenous levodopa across the whole brain, which must have some effect on other neurotransmitters. Levodopa does a good job with motor problems, but does little to address non-motor symptoms such as constipation. John
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Born 1955. Diagnosed PD 2005. Meds 2010-Nov 2016: Stalevo(75 mg) x 4, ropinirole xl 16 mg, rasagiline 1 mg Current meds: Stalevo(75 mg) x 5, ropinirole xl 8 mg, rasagiline 1 mg |
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"Thanks for this!" says: | jeffreyn (03-07-2018) |
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