I have had to move my doses closer together due to wearing off and having very uncomfortable dystonia. I take Sinemet every 3 hours along with requip and amantadine. I have tried the CR going to bed, Dr. thought it might get me through the night. I found it upset my stomach and didn't help much to get me through the night. I can see using it as well as the fast acting Sinemet but I wouldn't want to use it alone. The yellow zingers work best for me.

To those of you who take Sinemet CR, is it taken as an adjunct to the "regular" Sinemet or as monotherapy, i.e., as a supplement to the "regular" Sinemet? If you are taking Sinemet CR as a monotherapy, would you please give me your dosing schedule? If you're taking Sinemet CR as an adjunct to the "regular" Sinemet, would you please give me that dosing schedule. Doreen's neurologist's aim in prescribing Sinemet CR ONLY was to try to decrease the Sinemet-related dyskinesia(s)...which seems to have been accomplished on just 2 days of the
CR" only...BUT, her tremor has increased. I know...I know...it's very difficult to have it "both ways".

...and thank you so much to those of you who were kind enough to reply to my first post related to the Sinemet CR question...Vicky, TenaLouise, Paula and Evon. Paula...your thoughts, i.e., related to the Sinemet...less more frequently does seem more logical to me...and, in fact, Doreen was taking the "regular" Sinemet that way before her neurologist prescribed the Sinemet CR ONLY...and she seemed to be faring quite well on that regimen...as you said, too...more ability to control on this regimen.

We will see Doreen's neurologist this coming Friday, and once again, I will be "armed" with some information from the people here at this forum...thank you....

Therese