Carolyn, thanks for posting this study. Interesting finding in light of a notation in a small study by Abraham Lieberman reported in 2005 in which he compared 2 groups--one with PD and on statins and one group with PD and not on statins. though his findings were reported that the groups were "similar" in progression of their disease, there was a very interesting notation concerning 5 patients who were originally in the non statin group who were started on a statin during the trial. He noted that ALL 5 of these patients developed "worsening" of their PD symptoms after beginning a statin--which I assume means worsening of the disease or progression of the disease, though he did not make that distinction. the statins were stopped for 2 weeks in all these patients and because their symptoms did not regress to pre statin levels, they assumed the worsening of symptoms was not caused by statins--even though it is factual that the tissue half life of statins is unknown (vs plasma half life) and it is unknown the time required to re-establish normal levels of products blocked by statins other than cholesterol--ie dolichol, isoprenoid adenosine, selenoprotein N, coQ10. there was no further mention of this curious finding in the 5 patients started on statins in the study...

Parkinsonism Relat Disord. 2005 Mar;11(2):81-4.

Statins, cholesterol, Co-enzyme Q10, and Parkinson's disease.


Lieberman A, Lyons K, Levine J, Myerburg R.


Department of Neurology, University of Miami School of Medicine, Miami, FL
33136, USA. a...@parkinson.org