Unexplained Weakness

pabb · 09-23-2009, 07:33 AM

Quote:

Originally Posted by Macophile

Here is my full Drug List. However the Dr. does not think it is a drug side effect. It does weird me out though, cause I keep second guessing my body- like- does it really feel like that, or am I imagining it. I shouldn't do that, I know when something feels off, but I am so worried it will turn out to be another weird symptom that no-one knows what it is or what it means, and after a bunch of testing I will be back to square one. Or that it will turn out to be nothing (I know it sound wrong to wish it to be something, but when you are just waiting for symptoms so they can make a full Dx you want things to be something.

DRUG LIST

Migraine
1) Amitriptyline- 10mg tablet (6 at night)
2) Topamax- 100mg tablet (1 at night)
3) Magnesium- 500mg (1 at night)
4) Nerve Block (Occipital Nerve)- 9/11/09

Allergies/Asthma
1) Benadryl- 25mg caps (1-2 caps as needed.)
2) Singulair- 10mg tablet (1 at night)

Period Regulation
1) Solia- (Desogestrel 0.15mg, Ethinyl Estradiol 0.03mg) tab (1 at night)

High Blood Sugar (Important to note doc insists it is not diabetes)
1) Metformin- 500mg tablet (2 tabs- 2x a day- before breakfast & dinner, if >140 take 1, if >180 take 2.)

Irritable Bowel Syndrome/Acid Reflux
1) Florajen 3- 460mg caps (2-4 caps a day)
2) Flagyl- 250mg tablet (3 tabs a day)
3) Miralax- 1tsp daily
4) Protonix- 40mg tablet (1 tab a day, as needed)

Peripheral Neuropathy/Auto-Immune Disease
1) Gabapentin- 600mg tablet (5x a day)
2) Lyrica- 100mg caps (1 cap. 3x a day)
3) Baclofen- 10mg tablet (2 tabs. 3x a day)
4) Methotrexate- 2.5mg tablet (8 tabs per week)
5) Folic Acid- 1mg tablet (1 tab a day)
6) Vitamin D3- 1000IU tablet (1 tab daily)
7) Vitamin B12- 1000mcg tablet (1 tab daily)

flagyl can be nasty on the body, ...with the need of period regulation and BS issues...i would presume you have PCOS?..the D3 mrs D recommends the "oily" kind, which would be in capsules; perhaps a larger dose? Vit B12, on a totally empty stomache, and perhaps a larger dose, at least in the short term....was this new weakness shortly after your weekly methotrexate dose?
are you getting enough calcium?
good luck

mrsD · 09-23-2009, 07:49 AM

Methotrexate is a mitochondria poison. It used to be used as a chemo anticancer treatment. The use for inflammatory disease is somewhat different, but the drug effects remain the same.

http://www.mitochondrial.net/showabs...ondrial+damage

Since the mitochondria are the energy factories for our bodies' cells, damage to them, will damage tissue/muscle over time.
The trade-off is of reducing inflammatory response, vs killing the beneficial cells. One side effect of methotrexate is muscle weakness.

I put up a video on the vaccine thread here, yesterday. Dr. Cannell explains how Vit D prevents the body from attacking itself during viral infections. Since Vit D has been found very helpful for MS (an autoimmune disease), it is becoming more obvious every day that people with ANY autoimmune problem, who are making cytokines in excess which are attacking themselves, should have Vit D tested and take adequate doses to bring them up to normal levels.

Here is the video again:
http://www.youtube.com/watch?v=--NqqB2nhBE

While no studies show use of acetyl carnitine with methotrexate, carnitine is useful to prevent chemo cell damage in normal cells.

Macophile · 09-23-2009, 08:11 AM

Quote:

Originally Posted by pabb

flagyl can be nasty on the body, ...with the need of period regulation and BS issues...i would presume you have PCOS?..the D3 mrs D recommends the "oily" kind, which would be in capsules; perhaps a larger dose? Vit B12, on a totally empty stomache, and perhaps a larger dose, at least in the short term....was this new weakness shortly after your weekly methotrexate dose?
are you getting enough calcium?
good luck

The Flagyl can be nasty, but i only have to be on it sort term- thank heavens.

The endochrinologist also thought I had PCOS but I didn't quite meet all the requirements. (No excess hair, no cysts)

I am going to buy the "oily" vit D this week as I am almost out of the other one. And I will see if this does anything.

I do try to take the vit B12 on an empty stomache- I take it before I go to bed.

The new weekness started just before my next methotrexate does, not after.

And I try to make sure I get calcium.

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