--but they generally aren't the first things prescribed, as nerve pain is a different entity than nociceptive pain and they don't work for eveybody; anti-epileptics (such as gabapentin, pregabalin, and the like) and antidepressants are usually prescribed initially.

Does sound like you do have some potential causes in the work-up--you said you tested low in B12 (deficiency)? What were the numbers? (B12 deficiency can certainly cause neuropathic symptoms, and should prompt further testing for things like celiac/gluten sensitivity, iron and Vitamin D levels . . .)

Two things--one, make sure you get copies of ALL lab test results (including the nerve conduction studies); you not only want them for your records, but many doctors dismiss pertinent high or low results. Second, I don't know how complete a work-up you've had, but you can compare it to the Liza Jane spreadsheets, which were devised to be as exhaustive a list of possible tests for neuropathic symptoms as we could all come up with:

www.lizajane.org

Hello Cowboy,
I received more information here than from most doctors, have had this crap for over 5 years and have tried most of the pain meds. Have been on Methadone about 2 years and Lyrica for 4 years. To me less is best 10mg of Methadone and 100mg of Lyrica twice a day. Was on high dosage of Tramadol and Lyrica, fell a lot, cut off a finger working in my shop in '07 and developed breathing problems. I receive good care from VA, have to see a doctor every month for Methadone refill (IMO its the best just don't abuse it) Big side effect is constipation. Also take a good many supplements. I got PN shortly after taking Zocor for cholesterol (6 weeks). There are people here who can really give you good advice. Good Luck
Lanny

the lizajane site hasnt been working for a while.