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Old 01-10-2010, 08:42 AM #1
abbygirl abbygirl is offline
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Default Lymphoma
Anyone have SFN and then diagnosed with Lymphoma? I am only 42 and was diagnosed with SFN this past summer. I suffered for 3 years with burning in my feet and crampy calves. I finally have the pain under control with lyrica and cymbalta, but now am being tested with lymphoma. I just wonder if SFN could be a symptom of lymphoma? I have already had all other causes ruled out, but now I have some symptoms of lymphoma. Thanks
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Old 01-10-2010, 09:12 AM #2
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Lightbulb
Some cancers cause paraneoplastic neuropathy. The mechanism is not understood at this time.

Lymphoma is difficult to diagnose too. I hope you don't have it.
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Old 01-11-2010, 06:39 AM #3
glenntaj glenntaj is offline
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Default Unfortunaely--
--peripheral neuropathy symptoms are common among those with blood cancers, even before the chemotherapy regimens start (and these also can cause or exacerbate enuropathy symptoms).

The mechanisms are not completely understood, but have to do, it is thought, with autoimmune processes that cross react with components of peripheral nerve (blood cancers are at one level disorders of immune processes).

See:

http://neuromuscular.wustl.edu/nother/paraneo.htm

http://neuromuscular.wustl.edu/antibody/mprotein.htm
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