I had carpal tunnel with the foot PN severely with my low thyroid functions. Once that was fixed most of the carpal tunnel improved and so did my feet. I still have some, which is aggravated by some heavy working like gardening, so I splint my hands at night sometimes. I avoid surgery at all costs! My carpal tunnel got very bad during my pregnancy...that was frightening. But it resolved for the most part once my hormones returned to normal.

Fluid retention can also compress both the tarsal and carpal tunnel. So I suspect drugs like Neurontin and Lyrica could make this happen. Pre-diabetes also could be a culprit.
I think these compression issues, are mostly global in the body, so look for a metabolic trigger for yours.

I'm thinking that open wrist surgery for Carpa Tunnel could have negative post-operative consequences, but there is the laproscopic, less invasive type surgery to consider.
That's what I think I'll eventually have, when the cortisone shot- once every 10-12 mos, has no effect anymore.

Yes, some people who have wrist trauma and/or surgery develop RSD... afterwards. A visit to our RSD forum is enough to put fear in your heart!

But there is one study showing Vit C treatment when wrist injury was treated, reduced this risk:
500mg daily for 50 days!

I see the study was for fractures, not CTS, but they did hypothesize :
:.......Our hypothesis is that this beneficial effect of prophylaxis would be useful in other forms of trauma.".........

Couldn't hurt. Vit C has many other benefits, as well &
you cannot O.D. on it - excess is passed thru urine, I believe.
Could be useful for post operative CTS surgery recovery,
or maybe even help CTS symptoms without surgery?

I read somewhere that one of the reasons for CTS - is hormones imbalance which can occur during menopause which influence the all body.

I broke my humerus in 2000, in 4 places, right near the wrist....(xc skiing down icy hill, back when I did stupid things). Anyway, I would not doubt that did NOT help matters. I did not need surgery or screws, I was lucky. I was by myself and had to ski out a mile by myself and drive myself to the ER. I just kept the wrist splinted very close to my body and nothing moved. Lord. I could not do those things these days!

Anyway, likely that break made matters worse, but it is still bad bilaterally.