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Old 03-03-2010, 03:58 PM #1
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Thumbs down Mestinon

Has anyone here taken this medication? It is a drug used to treat Myesthenia Gravis but it was prescribed to help my autonomic neuropathy.

Well, the side effects are awful...

It is severely upsetting my already fragile GI tract. Stomach pain, cramps, diarrhea... you name it... I only took half the dosage (with food) as advised by the neuro. The thought of a higher dosage scares the hell out of me.

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Old 03-03-2010, 04:12 PM #2
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Question

This drug is used for myasthenia gravis, and is a acetylcholine agonist. It will increase your GI actions. I warned you of this when you mentioned it before.

I don't understand why your doctor gave it you? With your history, etc. What is it supposed to accomplish for you?
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Old 03-03-2010, 04:56 PM #3
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He said it may squelch the symptoms of my autonomic dysfunction...
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Old 03-03-2010, 05:29 PM #4
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Lightbulb

Well... it is pretty strong, and your reaction is quite typical.

There is one poster on MG forum who uses the liquid form.
That way you can accomplish lower doses. 60mg/5ml.

1ml = 12mg

However, this drug just might not be for you. Report this to the doctor, he may agree.
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Old 03-03-2010, 07:09 PM #5
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Thanks MrsD... I think I agree...I remember you mentioning that it causes gastric upset. I had no idea it would be this bad - with one dose of 40 mg. I can be a bit of a lightweight with meds.

At least I gave it a try...

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Old 03-03-2010, 07:13 PM #6
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Mestinon was the first drug I was ever on for PN. It was before I had my skin biopsy. It didn't do much but make me kinda sick and weird feeling....then again, every one is different. After I got my skin biopsy back, they put me on IVIG....(which I had my first reaction to this time--I'm fine, but I had some odd things.)

Anyway, one can always try the Mestinon...
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