I haven't spoken to the periodontist about it yet and cannot find any conclusive reports or evidence... other than a few people that could have been coincidental.
One poster says that it is an issue with all anti-seizure meds, but I cannot find any tests or results to that claim.
I really don't know if there's a connection. Pfizer would obviously deny it until someone other than them offered conclusive proof.
My age, previous perio issues before ever taking Lyrica, and being a smoker confuses the issue even more.

Hi. You may also want to ask your doc about increasing Cymbalta. I am on 120 and have been told some have to get to that dose for pain relief. Since you have found relief in the current you may have even more on a higher dose. I had bee o Lyrica but switched to neurontin. For me with most meds it takes awhile for the side effects to wear off. I get similar as you state with each increase of neurontin but with a few days to a week they go away. So if the side effects are tolerable but like nausea or spacy I try to give it a chance and stay in for those days. Of course if it is not tolerable then call the doc. Feel better

Yes, and it's pretty well-known that ANY med that causes dry mouth can be a culprit, so I reckon we'll never really know.
I've been on and off so many meds during the past, it would be too much of a long shot trying to pin it all on Lyrica, and I'd rather spend whatever remaining years I have on enjoying the good things in life!
Thanks for weighing in!

Yes, I agree.
But now I have to try to figure out how I'm gonna pay for all this dental treatment, surgery, and possible new full dentures. It could cost a 'pretty penny'. (and there isn't any really comprehensive dental ins to help me along with it significantly - I have a discount plan, but that's only about 25% of what my perio doc will allow).

I'm in the same boat basically. Have you spoke with Bryanna further on the full-denture issue? She's excellent at coaching us along. The full denture thing may not be as 'scary' as it sounds. Putting myself in your shoes, I would seriously consider opting for that.....it seems more cut and dry and
perhaps eliminating all that serious dental work you are facing right now.....may be a good investment for your future and saving you lots of $$ you'd currently pay out trying to save your teeth that are causing so much trouble....

I've recently heard several testimonies of those who ended up doing the full-mouth extraction and getting good dentures, had incredible improvement in their health issues.
???? Don't claim to know jack, but I'd certainly follow along a thread of Bryanna's on this issue if you pursued it.

Just my humble support and keeping your best interests to heart.... I know this is a huge issue for you....

P.S. to David .... didn't intend to 'hijack' your thread and turn it into a tooth issue! You are getting alot of good feedback on your thread, so I hope whatever you decide, it will work in your favor.....
best wishes!

Have idiopathic peripheral neuropathy and fibromyalgia. I've been taking Lyrica for about 4 years. Am up to 200 mg divided into two doses per day. Compared to Neurontin, Lyrica is a walk in the park. I ran out of Lyrica the other day and took 100mg of Neurontin and man oh man was I ever wiped out and dull-headed. Before Lyrica, I used to take Neurontin, about 900/day. I was taking it mostly for sleep disorder as my pain levels were not predominant. When I stopped taking Neurontin, I suddenly felt alive and realized that Neurontin had been sedating my brain way too much. Plus I found that I kept having to increase my dose in order to get the effect.

Lyrica is not like that, but I will say that I don't like the blurred vision I've experienced with this drug. And it is freekin' expensive.
BTW, I added Cymbalta to my Lyrica med program for about 4 months last year and it helped with the pain about 20 to 40%, but my memory was so bad--short term and memory lapses where I had no recollection at all of some events--that I could barely function at work. Also had terrible constipation which apparently is common. But the kicker is that I withdrew from Cymbalta over a week, which, evidently was to short. I experienced the most horrendous withdrawal: daily migraines, stabbing headaches, brain zaps, nausea which lasted over 6 weeks. My neuropathy is getting worse and I could increase my Lyrica, but I'm trying to hang in there for now.

I recently added 100mg of 5HTP and it is really helping me sleep--the more sleepy I am the better I can cope with pain--the less pain med I need. And I've lost about 8 pounds from taking 5HTP (and mood is better). Hope this helps.

I am unfamiliar with 5HTP
What is it?