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Old 06-11-2010, 11:51 AM #1
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Well small would be different for different people.

Typical PN doses start at 10 or 25mg. Some go to 50 etc.

The antidepressant doses are much higher, all over 150mg daily typically. I used to see 450mg sometimes in the old days even.
Getting really high with this drug is problematic because it prolongs QT in the heart. ODs are typically fatal therefore with amitriptyline, (whereas SSRIs are very much less so). Mixing high dose with other drugs that also affect the heart leads to possible problems too.

At your dose QT issues are not likely unless you have a genetic marker for it.
Here is my post on QT for you to read. The link to the University of Arizona that is on it, is very good and explains it well:
http://neurotalk.psychcentral.com/post15298-4.html
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Old 06-11-2010, 10:46 PM #2
Brian Brian is offline
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I was on 150 mg Endep at night, plus 25 mg in the morning for a few years, it was the only med I found that helped the burning the most, I stopped using it when I got better, so it definatly did not cause any nerve damage to me only helped a great deal.

good luck
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Old 06-14-2010, 04:54 AM #3
daniella daniella is offline
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Thanks I am glad you are feeling better though sorry for what this has caused. I have just started this med again. I am going to talk to my doctor about this. I believe that these things can happen from meds or what ever I just get confused on why one body it happens to and another it does not. I guess one person is more prone then another. Before this condition I was on meds for depression and anxiety and I never looked up side effects. The doc rx it and I took it. Now with each new med I research and don't feel as trusting. There was this comic on tv an was making fun of the prescription ads and how a person goes into the doctor asking for a certain med and it was so funny cause it was so true. I have tried many different meds by asking my doc after I read on here. The doctor is like sure we can try it. Anyhow sorry to get off track. Hope you get continued relief
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