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The following article suggests that "tricyclic antidepressants might deplete the body of coenzyme Q 10 (CoQ 10)." Perhaps a mechanism by which amitriptyline could cause neuropathy. BTW I have been taking it for a few years, mainly 25 mg/day, and it helps with my pain level. If it were slowly making it worse, I might never know. You can find alternatives, there are many drugs used to relieve painful neuropathy. It seems one of the premier ones is gabapentin (Neurontin).
I can't post links yet, so go to ** and search for "Tricyclic Antidepressants" "Coenzyme Q10(CoQ10) Preliminary evidence suggests that tricyclic antidepressants might deplete the body of coenzyme Q 10 (CoQ 10), a substance that appears to be important for normal heart function.1,2 Based on this observation, it has been suggested (but not proved) that CoQ 10 supplementation might help prevent the heart-related side effects that can occur with the use of tricyclic antidepressants." Good luck BasicPoke |
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"Thanks for this!" says: | DejaVu (06-18-2010) |
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