Thanks, I'll check out the diet (I'm taking D already). The only Rx drug I take is thyroid.

Make sure you are taking the right form of D==D3

And a dose sufficient to raise you up to 50-80ng/ml
Some doctors use 60ng as the high and other go higher.
But many doctors report low values as normal...like they do with B12. So it is important to get your B12 numbers too. For the same reason.

yes, thanks. I'm taking 6,000 iu of D3 per day.

Just so you know.... My PN came from untreated hypothyroidism for years... When my feet woke up...I was left with some residual numbness (and sometimes burning pain) in the tips of my toes.

Now that I am older, I have some insulin resistance on top of that.

Both my feet and hands were severely affected back then, and I don't think recovery for me to 100% was possible.

Hypothyroidism is known to affect compressive areas in the wrist and foot, where the ligaments are tight.

So you will want to make sure you are monitored properly with the thyroid testing. I keep my TSHs below 2.

Also you need to take the thyroid on an empty stomach to make sure it is absorbed well.

Mrs D or anyone when you say to watch soy,dairy,or gluten but if one does not have an intolerance I am confused on why that would make the PN worse. I know you and others said night shade increase your pain but I don't get the why behind this. Does it also damage the nerves? I understand it if you are intolerant the damage that can be done or if diabetitic. Same with meds on why one person could take a med and it not cause damage to the nerves and another it does. Could this happen with a med a person took as a child even and then it develop so many years later? If it is too hard to expalin I understand
I am sorry to ask so much on your thread. If I were you I would get a complete bloodwork done again if not recent. You may have to ask your doctor to test for auto immune,b,d etc,bloodsugar. That may give you more concrete direction.

When people have "leaky gut".... things pass into the body that shouldn't. This stimulates the immune system, and part of that involves inflammatory cytokines... including histamine.
It is this cascade of inflammation/histamine that causes the grief.

Also some peptides, being protein in nature can cause antibodies to be formed, and these can then attack parts of the body with protein sequences that are similar. Some reactions are confined to the joints, some skin, and some nerves, etc.

Many patients with autism for example cannot tolerate casein that is the peptide in dairy. So many autism treatments involve gluten free/casein free diets. Casein is thought to involve the central nervous system mostly.

Many are allergic to soy and some even corn. My son's friend from high school went deaf from corn. When that was uncovered in allergy testing, she went corn free and regained about 25% hearing, and now uses hearing aids. In her case the corn gluten, attacked the auditory nerves.

Everyone is different... genetics I guess determine what system will get attacked when allergies and intolerances exist.

Thank you for always taking the time to explain things so well. It is really appreciated and I have learned a lot here.

Thanks, that's interesting. I've been taking thyroid for several years (on an empty stomach) but this is the first I'd heard of any link to pn. Tests show now that my thyroid levels are fine, so I don't think that's it for me.