--you are saying that you had the immunofixation electrophoresis, and it came back negative for monoclonal antibodies (and light and heavy protein chains), but your overall immunoglobulins are elevated? That implies polycolonal antibody manufacture, which can mean a lot of things.

Yes, an IgA elevation may imply celiac, or some other gut situation, but not necessarily, as these are also secreted by mucosal membranes. And since elevated IgG implies a response to external pathogens over a long period of time (these are not as fast acting/fast produced as IgM class antibodies), assuming that these are not being produced erroneously (such as by rogue plasma cells) but accurately, there should be a search going on for low level infections, both bacterial and viral . . .have you had any infectious testing, such as a polymerase chain reaction, done?

Yes i had that test done by my neuro and the only this off is elevated igg.
He also did random urine with it.
My immunologist did a hiss panel that showed elevated iga, very high ige and elevated igg.

Never had that infectious testig. Which specialty showed I go to that can evaluate these new blood test as Neuro, gp, and allergist don't know what the elevation signifies!

Btw.. Great seeing you in YouTube :-)

So far in all my years of testing these ige, iga, igg are elevate Ali g with chronic elevated Sed rate and d vitamin deficient.

Glen can you expplain to me what I showed look for now.
You think there is some underlying infection or virus.
When I look my elevated IG it ALso points to cancers but all my other blood work is normal.

He immunologist did an extensive blood test for Lyme and DNA for Lyme.
Which is negative and he did Ana choice.

Glenn I see that immunologist did Lyme test but with it also lyme disease DNA, ql
Real time pcr, not detected

Is that chain test you are talking about. Would test cover all or each virus has it's own.

Thanks

Sorry for million questions.
Does elevated IG mean chronic or acute problems?
Thanks

--is the polymerase chain reaction test, to see if various infectious agents are in your sera--this can be done for any number of viral or bacterial pathogens (often depends on how many the doctor ordered; I once had one done for almost everything in the human herpes virus class, cytomegalovirus, parvovirus, and a whole batch of bacterial agents in one blood draw--all negative).

It should say on the test results what agents were tested for--each usually gets a seperate results entry.

That elevated IgG tends to imply a longer-term response than high levels of the other antibody classes--and in the absence of other cancer markers, particularly if there's a negative immunofixation electrophoresis result, one would tend to think infectious agent.

The pcr was only done for Lyme disease.
How can u ask my doc to do whole pcr of everything. Is there a specific name for that.
Thankyou
Glen