I have sciatica from lumbar disc pressure with terrific pain down my right leg and feet. Pain killers don't help. My doc is talking about an operation but I'd rather not. My cousin who suffers for years from diabetes with nerve pain told me she is taking Neurofencine with wonderful results. She says I should try it. This supplement contains g-agmatine. Does anybody have more information? I am desperate for a solution!
Iris

You might also copy this over to our Spinal forum for more input, they might have therapy ideas or other suggestions for the sciatica/lumbar disc pressure.
here is the link to it - http://neurotalk.psychcentral.com/forum22.html

This product is a derivative of l-arginine. (amino acid)

I think this is the study they refer to for "spinal pain relief"
http://www.ncbi.nlm.nih.gov/pubmed/20447305

This is what the website says:
http://www.fornervehealth.com/Resear...L_NERVE_HEALTH

There are many pages of studies on PubMed on this metabolite of arginine. But I could only find one human study on pain.

This product is being "re-launched" meaning it has been around for a while and now is being promoted again.

It appears to be quite expensive...at about $60 a month for the higher dose use.

So if you decide to try it, please let us know what you discover.
So far the website is using a graphic based on the experiments on bacteria and animals to promote use in humans. So IMO it is uncharted territory so far.

Thanks guys. I'll try the Spine link and hope for a quick response. Anyway, I think I will give this treatment a try.
Iris

Have you seen a pain management doctor? They can sometimes offer other treatments/procedures then meds and surgery.

In my experience with the pain mgmnt center at Hopkins, they are in the dept of anesthesiology and initially run a gamut of pain meds before considering any alternative recommendations or referrals to others. They are pill pushers.

I also suffer from chronic low back pain and I used to have unbelievable leg NERVE pain. Mine was in the front part of my thighs and stopped mostly at my knees. this was a burning pain whose only relief was sitting.

anyway, i tired it all for 3 years and finally had some surgery. best move i ever made. L2-3 laminectomy and almost immediate relief of that pain.

i also have L5-S1 pain in the back of my leg; tradidtional sciatic pain. but I currently control hat with cortisone shots about every 6 months.

Please consider Calmare therapy. I am pain free now. :-)