Question regarding small-fiber burning primarily in both palms

glenntaj · 09-22-2011, 07:11 AM

--for radiculopathy to cause issues with the larger, myelinated nerves, it is possible for compression issues in the spine to have effects on smaller, unmyelinated snesory nerves.

Many of these nerves originate from the dorsal root ganglia (which is where their cell bodies are--their axonal fibers can stretch out from there up to several feet), so if there are issues of compression around the dorsal root ganglia, often through posterior disc bulge, there may be small fiber effects.

drwk · 09-27-2011, 08:52 PM

Quote:

Originally Posted by glenntaj

--for radiculopathy to cause issues with the larger, myelinated nerves, it is possible for compression issues in the spine to have effects on smaller, unmyelinated snesory nerves.

Many of these nerves originate from the dorsal root ganglia (which is where their cell bodies are--their axonal fibers can stretch out from there up to several feet), so if there are issues of compression around the dorsal root ganglia, often through posterior disc bulge, there may be small fiber effects.

Hi Glenn! Is it possible for there to be posterior compression of the ganglion nerves that can cause widespread neuropathy. For example, it starts in the legs, then feet, then back, and then abdomen? It occurs in the matter of 4 months? Just curious. Thanks

glenntaj · 09-28-2011, 06:49 AM

--that a widespread neuropathy of that nature would more likely involve an autoimmune attack on the epitopes of the dorsal root ganglia.

But that doesn't mean that compressive issues might not also contribute--the so-called "double crush phenomenon". It is harder to imagine compressive forces being "equal" across that wide a range of spinal areas, though.

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