I now have hyperthyroidism from too much synthroid replacement (my thyroid was removed). So here is the problem: I started to have an increase in leg weakness about 2 to 3 weeks ago, I can no longer walk with just a cane and braces. My toes are numb and tingling an I lost most of the movement in my toes on my rt foot. I figure I have been hyper for about 2 months in order to have my hair start falling out and shaky tremors, all of the usual suspects. My levels: TSH .1, t3 20, t4 200, significant levels to cause symptoms. When I first had Grave's Disease I had leg weakness to the point of not being able to get out of a chair, do steps, and falling.

I see the Neuromuscular doc next week about my motor neuropathy. This is going to complicate my evaluation, IMHO. The changes in my meds will not kick in for at least 3 weeks. So I guess it will be back to wait and watch.

mrsD, L carnitine is supposed to help drop the levels of the t3 and t4. I am taking ALC 1000 mgs a day for about 3 months. Is this enough? I hate to think what my levels would be if I had not been taking this.

I'm looking around for verification....

So far I found this... Carnitine useful in both hyper and hypo states:

http://www.ncbi.nlm.nih.gov/pubmed/15803480
And this giving dose suggestions:
from:http://www.ncbi.nlm.nih.gov/pubmed/15591013

When taking carnitine, it is best to space out the doses, because there is a limit to GI absorption for each dose.

I saw one paper where the carnitine was given IV...for a thyroid storm (hyper).
http://www.ncbi.nlm.nih.gov/pubmed/21739342
This paper has no details or abstract tho.

This article goes into detail which might be helpful for you:
http://www.lef.org/magazine/mag2007/...thyroid_01.htm

What dose were you on, when this happened, if you don't mind sharing that?

This info is terrific. I was searching most of the am, guess I didn't hit the right keywords. Thank you. It is extremely helpful and I appreciate all you do. My husband says we never realized how many body systems can be ravaged by the thyroid.

I am taking ACL 1000 mg daily for about 3 months and synthroid 150 micrograms daily since mid January.

My dose was increased last December after several months of a TSH of 20! Docs have a bad time with my levels. I was still on the low side with the thyroid levels in April, so the elevation came on kind of fast.

I also take lipolic acid, lycine, b12, d3, c, krill oil, folic acid, thiamine in the doses you have suggested and as I have previously written to you, the horrible fatigue I was having was greatly reduced.

BTW my bloodwork was positive for Hashimoto's antibody. One of the docs said it was not important.

You sure have been thru alot! I really feel for you!

On our Autoimmune board are some posts about thyroid fluctuations. If you search Hashimoto's there you will find some posts there. I recall reading some posters here who had wild swings up and down.

With all are new medical advances it remains difficult to control the thyroid. I think if doctors were more open minded and listened carefully to the patients instead of doing cookbook medicine with test results only, there would be less suffering.