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Old 09-27-2011, 05:58 AM #5
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mrsD mrsD is offline
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mrsD mrsD is offline
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mrsD's Avatar
 
Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
Lightbulb

Okay, I found the supplement you are describing.

I think the dose recommended at 300mg is too high and not necessary.
Even at one capsule, 100mg is high.

Most people don't need that much B6 in ANY form.

Here is an alternative example... one a day.
http://www.iherb.com/Now-Foods-P-5-P...blets/740?at=0
I believe the main action of Metanx is the methylB12 in it.
Folate is not that critical in PNers, unless they have the genetic mutation MTHFR... which is about 10% of the population.
The methyl folate then is useful for those people.
The activated B6 is useful for people low in B2 which is needed to activate pyridoxal kinase --which is the enzyme that activates pyridoxine.

Notice that P5P by NOW is enteric coated...that is for a good reason.
Take methylcobalamin (methylB12) always on an empty stomach. With that high B12 in Metanx I'd expect you to be higher than you are. But you are high enough for most purposes as it is. My B12 went up to 1999 (test max) on 5mg of methylB12 on an empty stomach, for 3 months of Puritan's Pride version...for pennies a day.

It is possible to do this yourself for far less $$.

You can always reach me via PM. I think you are active for this function now.
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Last edited by mrsD; 09-27-2011 at 06:19 AM.
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