that the spot need to be taken seriously. The twitching may turn out to be benign, buy fasiculations as they are called, are judged by the company they keep, and a spot on the brain is bad company. You probably should see a neuromuscular specialist.

So my understanding is that MS is more than one lesion. I have 1 lesion that is 3 mm. Can anyone tell me what else this could be? I've heard migraines, low b12, but what other neurological conditions could this be tied to?

Thanks!

Some lesions come from contaminated food ... certain parasites, can enter the brain. There is a specific worm called the pork tapeworm that enters the brain. Lyme disease is also a parasite. Some viruses like Herpes, zoster (chicken pox and shingles), low B12.

Here is a medical Mayo article about it:
http://www.mayoclinic.com/health/brain-lesions/MY00847

After reading the MS forum for a long time I've seen posts where people have follow up MRIs and some lesions go away.

Annie if you get any answers could you let me know?? I started with buzzing in my feet about 4 yrs ago. I would get cold feet in winter ICE BLOCKS and had some burning. My issues are much like yours, I have had a nerve here or there buzz for days and have had muscle spasms as well in various areas on and off. This has now spread in arms and legs --I feel jittery and have the internal vibes as well. I have no explanation why except I do have a back that is not good. I sure would be interested to know if you get any answers. I also developed jerking in the am so having getting a brain MRI I do have migraines so think lesions will show. I am not getting one with contrast so hope what will show up will... Thanks

Hi Annie4

I can relate to so many of your symptoms and my neurologist is doing everything in her power to determine a diagnosis after 9 years.

I had a lumber puncture done just last week and oligoclonal bands were detected in my spinal fluid, which is a substance in multiple sclerosis patients, but my neurologist is convinced I don't fit the profile for MS although I have so many symptoms related to it. We are however a step closer to a diagnosis after the LP was performed. I fully suggest you have a LP done. It can provide so many unanswered questions.

Same at you, I also have a lesion which was detected through an MRI, which is located on the left side of my brain and all these other symptoms related to weakened, burning muscles and nerve losses, even in my right eye.

I did however November 2004 had a supposedly Thalamic Stroke. I woke up one morning with my entire right side paralysed.

The anxiety I can relate to also and my neurologist now for the first time prescribed me Zanor and increased my Effexor (which was initially given together with Epleptin (Gabapentin) for the muscle burning and weakness). You can also request from your neurologist something for the anxiety as it can be caused by the decease you are suffering from.

Please hang in there and I keep thumbs up that you'll get a diagnosis soon with proper treatment. Please keep us updated also and thank you for sharing.

Annie hasnt been here for 2 1/2 years.