I had the skin punch biopsy test done at the Cleveland Clinic. Sites were lateral side, just above the ankle. Lateral side, just above the knee and lateral side of the hip. Have never had this done before and there were no unusual biopsy sites. Knee and hip were negative. Ankle / lower calf tested positive. Any questions, fire away. I am an open book.......anything to try and conquer this beast!!

Hello. Just wanted to say I've just had the SFN Skin Punch done by my Neuro at HSS in NYC by Therapath. On the form I saw that one may take from three sites, she only took from two the upper thigh and the side of my ankle She did not take from the side of the foot. When I asked her why (since my pain is at the bottoms of my feet....heat, stinging , walking on broken glass etc) she said "here at HSS we do two places" as if that answered the question. When I asked what we would do if this was negative , what would explain 13 years of maddening pain, she said "Let's not go there.... your symptoms are certainly in line with SFN".

Well, the results were negative. EMGs were negative. no idea why i have this.
I am next going to see a Rhematologist but not sure what we are looking for.

Frustrating.

Your background sounds strangely familiar, I have all the same issues with the feet and back, now my bottom too. Hope things get better for you, this started for me in May and it has continued to progress with no know cause.
1) Which testing lab? John Hopskins
2) Where was your sample taken from? outer calf and outer thigh
3) Your diagnosis before or after the test? No diagnosis yet
4) Your result (just pos or neg) and/or results for multiple tests if done more than once? Negative
5) Has anyone had a sample taken from an area 'other' than the typical areas suggested in the test kit? No

1) Which testing lab? Therapath
2) Where was your sample taken from? top of foot and front of upper thigh
3) Your diagnosis before or after the test? Tentative diagnosis confirmed by biopsy

My SPB was done in 2006. My neurologist suspected I had small fiber neuropathy because my symptoms far exceeds what the EMG indicated as problematic. From my lab report:
Any value that is equal to the fifth percentile or less is considered to be significantly reduced nerve fiber density, consistent with small fiber neuropathy. The fifth percentile value for the distal leg is 5.0 per mm.
My value was 0.07.
My neurologist said that I had very few nerve fibers left in my feet. After extensive testing, it was confirmed that my neuropathy was a rare extraintestinal manifestation of my Crohn's disease.

Hi, this is my first post. I had skin biopsy done at OU Campus Neuro office Oklahoma City. They took it at Left ankle and L hip. Those were Neg. Then my Neuro had them do the sweat gland nerve fiber density test. This came back with significantly reduced sweat gland nerve fiber density, consistent with small Fiber neuropathy. The lab was Therapath, New York.I also was diag. with Autonomic Neuropathy.

I was so glad to finally get a diag. Symptoms were electrical shocks in feet, hands, face, mouth. Burning in feet, pins, needles. All the Autonomic symptoms also. It's a real drag. I had to quit my job and am in the middle of trying to S.S. I take Neurotin, 600mg 4x day. Methadone, I go to a pain clinic, Cymblata 60mg day, Baclofen 20mg 4x day.

I hope this may help you in some way.
God bless...