PN and now RSD from broken radius

mrsD · 04-09-2012, 10:01 AM

In UK and France they are using high dose Vit C to prevent RSD in wrist and ankle surgeries/trauma. (1000mg a day)

Here is an example of a paper...

Quote:

Foot Ankle Surg. 2009;15(4):179-82. Epub 2009 Apr 5.
Effect of vitamin C on prevention of complex regional pain syndrome type I in foot and ankle surgery.
Besse JL, Gadeyne S, Galand-Desmé S, Lerat JL, Moyen B.
Source

Université de Lyon, Lyon, France. jean-luc.besse@chu-lyon.fr
Abstract
BACKGROUND:

The public health cost impact of complex regional pain syndrome type I (CRPS I) is considerable in both emergency and scheduled orthopaedic surgery. We proposed to assess the effectiveness of vitamin C in prevention of CRPS I in foot and ankle surgery.
METHODS:

We carried out a "before-after" quasi-experimental study comparing two chronologically successive groups without (Group I: July 2002-June 2003) and with (Group II: July 2003-June 2004) preventive 1g daily vitamin C treatment. All patients having surgery on the foot or ankle were enrolled, with the exception of diabetic foot cases. Several factors were analysed: sex, age, type of pathology, history of CRPS I, psychological context, tourniquet time, and cast immobilisation time.
RESULTS:

420 feet (392 patients) were included in the study: 185 in Group I, 235 in Group II. CRPS I occurred in 18 cases in Group I (9.6%) and 4 cases in Group II (1.7%) (p<10(-4)), with history of CRPS I as a significantly correlated factor (relative risk=10.4). The psychological context (anxio-depressive state) showed a (sub-significant) tendency to increase the risk of CRPS I (relative risk=2.6).
CONCLUSION:

Vitamin C has been shown to be effective in preventing CRPS I secondary to wrist fracture, but few data are available with respect to foot and ankle cases. The present study demonstrates the effectiveness of vitamin C in preventing CRPS I of the foot and ankle-a frequent complication in our control group (9.6%). The authors recommend preventive management by vitamin C.
Comment in

Foot Ankle Surg. 2011 Sep;17(3):207.

PMID:
19840748
[PubMed - indexed for MEDLINE]

If you click on PubMed link at the top of the page and type this keyword into the search there you'll find other papers discussing this:
"reflex sympathetic dystrophy vitamin C"

Our RSD forum also has a vitamin C thread:
http://neurotalk.psychcentral.com/sh...ight=liposomal

RSD is complicated and you might want to visit our RSD forum:
http://neurotalk.psychcentral.com/forum21.html

They are also discussing a new electrical treatment called tTCS there:
http://neurotalk.psychcentral.com/thread160980.html

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