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Old 05-12-2012, 10:18 PM #1
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I just did a lot of reading about it. Lots of problems with many antibiotics and that one is one that a lot of people have problems with, just my feeling.
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Old 05-13-2012, 08:31 AM #2
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I just did a lot of reading about it. Lots of problems with many antibiotics and that one is one that a lot of people have problems with, just my feeling.
Here is a medical article I found:

http://www.medlink.com/medlinkcontent.asp
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Old 05-13-2012, 08:34 AM #3
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I just did a lot of reading about it. Lots of problems with many antibiotics and that one is one that a lot of people have problems with, just my feeling.
I found this part of the study interesting:

Onset may be insidious, subacute, or acute, and symptoms typically progress if the antibiotic is continued. In most cases, symptoms improve or resolve after the drug is discontinued. This, as well as the temporal correlation of symptom onset and the use of the medication, serves to strengthen the causal association. In some cases, as with isoniazid, recovery can be slow and incomplete, especially after prolonged use.



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Old 05-13-2012, 11:46 AM #4
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Isoniazid causes a "neuropathy" due to the fact it depletes B6.

When B6 is given with it (which it almost always is), this neuropathy does not manifest.
http://en.wikipedia.org/wiki/Pyridoxine

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Pyridoxine is given to patients taking Isoniazid (INH) to combat the toxic side effects of the drug. It is given 10–50 mg/day to patients on to prevent peripheral neuropathy and CNS effects that are associated with the use of INH.
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Old 05-13-2012, 01:26 PM #5
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Isoniazid causes a "neuropathy" due to the fact it depletes B6.

When B6 is given with it (which it almost always is), this neuropathy does not manifest.
http://en.wikipedia.org/wiki/Pyridoxine
Interesting. I was on isoniazid as a child for a few years because my mom had TB when she was young, and she could never be convinced that she wasn't contagious anymore. Interestingly she took B-6 with it, but I didn't.
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Old 05-13-2012, 03:55 PM #6
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Found this and thought it was intereseting.


http://www.livestrong.com/article/43...sis-treatment/
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Old 05-13-2012, 06:58 PM #7
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Originally Posted by mrsD View Post
Isoniazid causes a "neuropathy" due to the fact it depletes B6.

When B6 is given with it (which it almost always is), this neuropathy does not manifest.
http://en.wikipedia.org/wiki/Pyridoxine
I was diagnosed with Ileocecal TB in 2000 or 2001. I was on treatment supposedly for 6 months but because of nausea and vomitting, my dosage was adjusted up and down depending on my tolerance. So, the whole course was extended to 9 months.

I forgot the name of the antibiotic I was on.

Assuming the TB medication is the cause of my PN, does it take 10 years to show the symptoms of the damage?
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Old 05-13-2012, 08:30 PM #8
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Quote:
Here is a medical article I found:

http://www.medlink.com/medlinkcontent.asp
I cannot see the link.
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Old 05-14-2012, 05:04 AM #9
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I cannot see the link.
When you go to that link, you have to put in the search box in the upper left, "fluoroquinolones" . The first article that comes up is the one listing the drugs. That site has a strict copyright rule so we cannot copy that information here.

Some websites do not give individual addresses to their sub categories. This is one of those. The FDA.gov is another.
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Last edited by mrsD; 05-14-2012 at 02:27 PM. Reason: fixing spelling
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Old 05-14-2012, 07:27 AM #10
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Originally Posted by Idiopathic PN View Post
I was diagnosed with Ileocecal TB in 2000 or 2001. I was on treatment supposedly for 6 months but because of nausea and vomitting, my dosage was adjusted up and down depending on my tolerance. So, the whole course was extended to 9 months.

I forgot the name of the antibiotic I was on.

Assuming the TB medication is the cause of my PN, does it take 10 years to show the symptoms of the damage?
It would depend on what you took. Some of the drugs are harsher than others.
http://en.wikipedia.org/wiki/Rifampicin
This drug is often combined with isoniazid.
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