Hello i posted earlier (called "peripheral neuropathy" - basic symptoms are tingling in legs, tripping, foot dragging) after 6 MRIs, an EMG/NCV, VEP (all normal), and a neurological exam (basics) my neuro has recommended me to a neurologist who specializes in hereditary neuropathies (my grandma has PN and cant feel ANYTHING from knees down). I am very frustrated because this new doc has no open apts until frebruary (At which point i will be back at school). anyway i have a few questions...

1. Anyone with smal fiber neuropathy or CMT .. what are the early symptoms of these? (my symptoms right now seem to be very mild)
2. What neuro disorders can be triggered by stress (all of my tingling has occured during stressfull periods of time).(either of the above)

Check out my forum concerning CMT at the top of the page under "PN Tips, Resources, Supplements and Other Treatments". There are many many types of CMT. Symptoms of CMT can become evident when you are young, old, or in-between. Or symptoms might not be that evident.

CMT has been and still can be misdiagnosed as something else. The fact that your Grandmother has PN and cannot feel anything from her knees down is interesting. There are many types of PN out there. Does anyone else in your family have anything similar? Hopefully you will get an answer soon. An expert neurologist who knows CMT might be in order in the initial diagnosis if indeed CMT is suspected.

February is a long time to have to wait. Perhaps you could find another doctor.

also both my emg and ncv were normal (according to my neuro) does this rule out CMT?

Not necessarily. When the myelin is damaged (CMT1) the nerve impulses are conducted more slowly than normal. If the axon itself is damaged (CMT2) the speed of nerve conduction is almost normal, but the strength of the signal is reduced. All forms of CMT are either demyelinating or axonal in nature. CMT is a multi-gene disorder and so there are many different defective genes which cause the disorder.

CMT affects the peripheral nervous system (PNS) and therefore it results in both motor symptoms (weakness and muscle wasting) and sensory symptoms (numbness). CMT is progressive and usually slowly.

Hope this helps.

Early symptoms,from childhood, for me were being unable to run, skate, or play sports. Also high arches and weak ankles. I have always been very clumsy and accident prone. My sister wore braces for drop foot fom early childhood. I did not develop numbness until my early 30's, but it has progressed from my toes to above my knees, like your grandmother. I am now 50. I have had progressively more pain and weakness in my legs, as well as my hands and arms, as the years have gone by, and the symptoms have really accelerated in the past three years. I walk with a cane, and am losing the ability to go up stairs.
As Kitt said, everyone's symptoms, onset, and progress are different. I have CMT type 2, axonal degneration. My EMG/NCS is abnormal and shows large fiber neuropathy, my skin punch biopsy shows an advanced small fiber neuropathy. I have very limited ability to move my toes, and there is visible wasting of the muscles in my feet and lower legs.

hmmm when i was a kid i was prone to falling alot (and ending up on my face)but i am currently a runner ... do small fiber neuropathy or CMT become worse during stressful times? thanks so much