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Old 07-17-2012, 08:55 PM #1
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mrsD mrsD is offline
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mrsD mrsD is offline
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Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
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There are studies to show acetyl carnitine helps with chemo induced PN.

It is best started when you have the chemo... but I'd try it anyway. It helps with mitochondria damage from the chemo drugs.

Start at 500mg a day and slowly raise by 500mg once a week to 2 grams. You may see some improvement at lower doses, but 2 grams a day is one dose used in the studies. Take in divided doses because this supplement is not well absorbed. Dividing it up may get more into your blood stream.

There is a better form of lipoic acid... called R-lipoic stabilized.
This only needs 100mg a day for most people.

This is one of many posts on lipoic acid here:
http://neurotalk.psychcentral.com/sh...ht=lipoic+acid
If you use the search function you can see many more.
This thread in particular is where we discover new information about the stabilized form. The "old" alpha lipoic is a mixture of R and S and the S form is not active. Hence you need high doses. And all lipoics should be taken on an empty stomach for best absorption. If you take with food you may reduce absorption up to 30%.

B12 should ideally be tested. You should get the numbers as labs here in US are outdated and reporting LOWs as normal.
Doctors don't know the difference and people with lows get missed and continue on with damage from low B12.

If you test below 400, then an inexpensive methylcobalamin daily may help. This can cost you about 10 cents a day.
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