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Old 10-15-2012, 06:10 AM #17
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mrsD mrsD is offline
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mrsD mrsD is offline
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Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
Lightbulb

Joe, the best way to ferret out a problem is to be a detective of sorts.

Your cyclical fever suggests an infectious trigger. There is a tick borne disease called babeiosis, which resembles your initial symptoms. But it is not commonly found everywhere, so I don't know if you travel, hike, camp in the woods alot, etc.
Babeiosis also has a hemolytic anemia, and you don't mention that aspect at all. So it is only a shot in the dark.
There is also the West Nile Virus, which causes encephalitis too, but I don't know if your area has this. We are having an outbreak where I live this year, in fact.

But the ME potential is also thought to be triggered by an infectious process too. Many viral problems turn up here as PN's later. It is a theory that the antibodies in us, may find other tissue that resembles parts of the virus and also attack it. It is called molecular mimicry. The fatty axons of nerves seem a prime target.

Now in YOUR case with the addition of the statin, you may have exaggerated response. This is because we now know from recent studies that statins block the nerve growth factors that repair nerves. At one time the anti-inflammatory suggested traits of statins, lent them to be studied for MS patients. The thinking was that the statins may block the formation of the damage plaques in the brain, that are seen on MRIs. But in reality what happened was it was discovered that statins blocked the regeneration of damaged nerves instead. So the statins trials for MS were discontinued.
This is a link to that information. Our PD forum is pretty active in posting statin information, BTW.
http://neurotalk.psychcentral.com/sh...=remyelination

So in effect the damage from an environmental assault on your nerves could be compounded by your statin use. It is something to think about. Statin information now is very available since the patents are running out quickly. Once all of them are on generic, we'll see more papers released. Big Pharma has a habit of holding negative papers for a long time, so as to get as much money as possible from the drugs. This was the case in estrogen therapy for menopause (mostly in US) and also antidepressants, esp studies on children.

There is a member here named Peter. His daughter has ME and has made a wonderful website I think you should look up.
http://www.hfme.org/

and her new site still being worked on:
http://www.hhhummingbirds.com/

The HFME site explains the difference between ME and CFS.

Another thing I found, that might be of interest to you is
Transverse Myelitis. This is an acute spinal inflammation that follows infections, and/or the use of some drugs. (fluoroquinolone antibiotics may cause this)
However, the symptom presentation, on the websites listed is confusing and I am not a neurologist, so I cannot interpret it completely. But it is something to check on and discuss with the doctor. It can often be confused with MS.
http://en.wikipedia.org/wiki/Transverse_myelitis

Typical diabetic PN type does not present suddenly like yours, or affect muscles so quickly. The acute PNs like CIDP do and can affect motor earlier as demyelination will be global.
Your tests on Friday may reveal more for you. If you are diagnosed with a demyelinating form, you will have to consider stopping that statin...as it is adding to the problem.

In the meantime, I'd start the magnesium ASAP and see if your muscles improve. Magnesium glycinate is one type of chelate that is well absorbed.
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Last edited by mrsD; 10-15-2012 at 06:45 AM.
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