Combining supplements has worked well for me. I have integrative MD's that know doses and great brands and what works together. I get blood tests several times a year. Do you have a good doctor to guide you?

I have a schedule, supplements to take three times a day

I hope you continue to improve.

Agreed. I'm going to give this time, even if there are temporary setbacks etc.

Not in that she is an expert in PN - she's a GP after all - but in that she is willing to work with me, takes my suggestions into consideration, and keeps me from making mistakes/follows up what I'm doing. All things considered I think that is positive. She's also given me the details of a good neurologist, but at the moment I'm not sure if it's useful to schedule an appointment; I'm not sure what he/she could do for me, to be honest.

Thanks.

I have one suggestion... take the biotin away from the lipoic...space them out. When the B5 comes, that too.

B5, biotin and lipoic all share the same transporter in the blood.
If you take them together there may be too much competition for it and some of the doses may be lost.

Because the biotin is so strong, you could take it on alternate days, that way it would be less likely to compete.

The doctor supervision is important for monitoring kidney functions.

Aha. Thanks for that. I already spaced the lipoic acid away to an hour before my evening meal. Will take the B5 late at night then.

Oh absolutely! We have a schedule to test my blood every 3 months to monitor kidney/liver/vit B12/D/thyroid etc.

I do understand that many of these vitamins are "harmless" only if your kidneys fully function. A friend of mine had a serious kidney failure a couple of days ago, and decided to go on a vegetarian diet. I did mention B12 to her, but had no idea on how that could build up if your kidneys only work at 35%... I suppose that changes a lot of things.

Thanks again for the tip about spreading those 3 apart.