Hi.

I'm sure this question has been asked/addressed numerous times on here, but is there a "standard" dosing amount for methyl b12 for peripheral neuropathy? One other thing, I had my b12 level checked a year ago and it was 530 something if I recall.

Seems like I've read some conflicting things on this question, in terms of whether it's advised to do 1000mcg daily or 5000mcg daily?

Thanks.

530 is rather borderline. So I'd do 5mg of methylB12 daily on an empty stomach for 3 months. Then get checked again.

If you are over 1000 then you can cut back to 1mg a day.
At 1mg a day you absorb about 13mcg passively from that dose.
Enough to keep going, but not really high enough to fix things
that may be running poorly. B12 gets stored in the liver and crosses into the cerebral spinal fluid quite a bit, so when you are really low then those areas can take up alot of each dose. Once you hit a steady state there and in the tissues, then you can maintain
at lower dosing. But basically 5mg is not a whole lot daily either, and since B12 is rather benign it won't be harmful to continue with it at that level either. That part is up to you.

Thanks, mrsD. I believe it is your belief that the oral is just as good to take as the sublingual, or am I incorrect in that?

Ooops. Sorry, I see that this was all addressed in the sticky at the top of the page.

Yes. Even studies show that they give the same results on testing.

I really think the sublinguals are swallowed in the saliva.
But for those who "believe" they work, those individuals should
do so under the tongue on an empty stomach (just to be sure).

The B12 molecule is huge, and not lipophilic and not likely to
cross the small area under the tongue reliably IMO.

Daily oral use is closest to nature too. We were not evolved to
get mega shots every month. But to eat animal derived foods on a regular basis. The study I have linked to in the B12 thread here even shows that the injections only provide about 150mcg per 1000 shot anyway. One would think more but I guess it is excreted as a huge mega dose quickly. I read once within 72 hours. That is why people show up online with injection roller coaster side effects...up and down, feeling great feeling terrible the next day, etc.

Just went to the shop and picked some up (Jarrow's 5000mcg). MrsD, this is going to be a dumb question, but I just chewed it up and swallowed it...I assume this is the way to take it orally as opposed to swallowing the pill whole with water?

Thanks, just want to make sure I'm taking this right.

Yep, I chew them up too. No food for at least an hour after, to assure best absorption.

It is amazing how important this is, and we are so fortunate to have OTC access without inflated prices! So much for so little!