Does your lab report give the ranges for that lab with the results?

This can be important, because of lab procedures and calibration.

If you are in US 444 for B12 is just barely normal. The lowest normal now is considered to be 400pg/ml.

Your MMA level seems odd.
From the net:
The reference range of MMA is 0-0.4 µmol/L (0-4.7 µg/dL).
from http://emedicine.medscape.com/article/2108967-overview

Elevated MMA indicates that B12 is not working in the body, so the MMA builds up. One wants to see a very low number for MMA, therefore.

This link gives arsenic ranges:
http://www.atsdr.cdc.gov/toxguides/toxguide-2.pdf

So your arsenic level needs explanation.

Your magnesium is in the low end of normal.
http://www.nlm.nih.gov/medlineplus/e...cle/003487.htm
This is common in the US where 70% of Americans show
some low magnesium levels.
So eating more foods that contain it, and avoiding diuretics like alcohol and caffeine, and diuretic drugs, may help that.
You can take a supplement like SlowMag twice a day. Or soak in epsom salt baths.

Your folate is elevated:
http://www.everydayhealth.com/health...d-results.aspx
This is common when there are B12 problems.

You may not be methylating B12 and folic acid properly.

So you can start taking methylcobalamin and methylfolate OTC and see if that helps. Most doctors will not suggest anything with your test result. they are not aware of the new guidelines.

Folic acid is in fortified foods now in the US. If you cannot methylate (activate to folate) either, then it will build up in the serum. This failure is a genetic error and pretty common. Left untreated it can lead to cardiovascular damage and disease.

There is a DNA test for MTHFR genetic polymorphism if you care to delve more deeply into it.

Do the magnesium because it is really helpful for most people.
Here is my magnesium thread.
http://neurotalk.psychcentral.com/thread1138.html

Methylcobalamin: 5mg daily orally on an empty stomach. Do for 3 months, and evaluate results. Your levels should be over 1000.

Methylfolate: Metafolin by Solgar, 800mcg a day to start.

Both of these are available online, example:
iherb.com

Test Range Units
Esrman=1 0-15 mm/hr
CRPHS= 3.9H 0-3.0 mg/L
MG= 1.9 1.8-2.4 mg/dL
FOLATE= >19.9 >3.0->3.0 ng/mL
RPR**********
VITB12= 444 211-946 pg/mL
HIVINDEX= <1.00 <1.00
HIV QUAL******
PROT,S= 6.7 6.0-8.5 g/dL
ALB,SER= 4.2 3.2-5.6 g/dL
A1 GLOB,S= .2 0.1-0.4 g/dL
A2 GLOB,S= .7 0.4-1.2 g/dL
BGLOB,S= 1.0 0.6-1.3 g/dL
GGLOB,S .7 0.5-1.6 g/dL
MSPIKE=*******
GLOB,S= 2.5 2.0-4.5 g/dL
A/GRAT= 1.7 0.7-2.0
PLS NOTE= Comment
ARSENIC= 5 2-23 ug/L
LEADBLD= None Detected 0-19 ug/dL
MERTCBLD= None Detected 0.0-14.9 ug/L
MMA= 111 73-376 nmo1/L

mrsD, I went to wal mart today and got some Slowmag, I'm looking into the Pharmagaba( I went to an herbal store in town and it was outrageous so I'm going to do some online shopping). As for my vitamin b level, I would like to bring it up would you recommend b-complex or just regular b-12 for that? As far as all the other tests go I am going to take your advice and get the other products online as well. I plan to take all this information to my doctor and hopefully he will comply with the steps I want to take, if not I guess I'll go doctor shopping again. Is there any other lab work I should request? I'm going to write down the levels suggested on some of the links on this forum and go every 3 months to make sure I'm maintaining levels that I want, and hopefully from cutting the caffeine, alcohol, and stress and maintaining a healthy diet (cutting fast food) I can get back to my normal self again. And this is probably an obvious question but I'm still new to this, if my conditions are from alcohol, poor nutrition, and anxiety, if i fix all these things will my "neuropathy" revere, or is this an irreversible cause?
And is there a suggested book or website that will give me a complete 100% guide of a great healthy diet, not for weight loss, just all around good health?

Alot is unknown about PN. This why you are HERE, and why your doctor is not helping you.

Your lab range for B12 is the outdated old one, where lows are
in the 200 range and called "normal". This is unacceptable.

We have tons of information gathered here on the Subforum and on the B12 thread and some at the vitamin forum.

To start you need to up your B12 to a level at least of 1000.
Use Methylcobalamin 5mg orally on an empty stomach, for about 3 months and get retested.

Start the magnesium, and with both of those see how things go.

Avoid sugar, MSG, and gluten if possible. There are over 100 types of PN, and you have to approach this carefully and with thought.

You could have a hereditary CMT. At this point you just don't know. Try to relax, do meditation exercises, and keep your brain off your discomforts. If you focus on them they will burn a pathway to your pain centers and become self perpetuating.
This is the new way to approach chronic pain. Do not allow your brain to train itself to focus on discomforts. You can Google and find these techniques, for many types of pain.

Thanks mrsD, I probably speak for everyone when I say I'm so thankful your on here and willing to help everyone.

This is great info, as I am in the same boat. Dr gave me 1 cc B12 injection per month seems to help for a few days after the shot so now I take 2 per month.along with a good multi vitamin,omega-3,B-1 300,Magnesium 250,Niacin 500 and Acetyl-L-Carnitine 500,alpha-Lipoic Acid 200.Thinking it is due to alcohol I wonder if I need something else .All the vitamins I had to figure out on my own except the injection .This with Gabapentin 300x4,oxy condone 5x3 and Amitriptyline 150 at bedtime.It helps somewhat but doesn't touch the severe flare ups that can last for days.I live in constant pain if I can knock it down a little more I am open for anything! Sometimes I can barely walk, need help it has took my life away.I am great full I found you guys since I have been praying for guidance ! I know you guys know what I am going through.I would not wish this on anybody but it is nice to know I am not alone. With all the very informed and knowledgable people here gives me hope that I had lost along time ago.Thanks so much!

Welcome to NeuroTalk, Beachbum...

You are off to a good start. But check that magnesium and
make sure it is NOT OXIDE form. That type is not absorbed and is passed in the stool.

I think you would do better on active methylcobalamin oral 5mg a day on an empty stomach. The shots don't work well for everyone and they are not the activated type of B12 either, unless you get them compounded especially for you.

Anyone who drinks alcohol or suspects a connection with alcohol should try the improved B1 called benfotiamine. You can get this at iherb.com or Amazon. Most of us use the Doctor's Best brand. Start at 300mg a day and see what happens. After 3 months or so you can drop to 150, if your improvements sustain.

People getting B12 shots should have testing done to see if they are really working. Don't do any shot or supplement for 7 days before the test. You should be above 400pg/ml...which is the new cut off point for "normal". Don't accept "normal" comments from a doctor. Get your own numbers.

Thank you mrsD. I go in for lab work again this week I will get the numbers , that's exactly what they said your "normal" last time! Since I have been taking shots and vitamins I will reschedule for a later date. Benfotiamine 300 a day I will order some, thank you for the info. This may seem to be a stupid question but as a long time drinker I also smoke cigarettes ,haven't kicked that habit yet but have cut way back. Is is possible that cigarettes causes neuropathy? I know it can't help but it calms my nerves on the outside. My neurologist said I have sensory neuropathy and it was most likely permanent and may get worse. Probably have had this 4 to 5 years hard to say for sure but it started as a tickle in my feet changed to pain and slowly crawled up my legs. I have no reflexes with the rubber mallet on my knees and in the bend of my arms, not sure what to make of that. Thanks again

I have some more lab results from last summer. I also have some lab tests taken a couple weeks ago. Here they are.

** These are from last summer **
Metabolic Panel Result Range
Glucose, Serum 83 65-99
BUN .79 .76-1.27
eGFR If NonAfricn Am 125 mL/min/1.73 >59
eGFR If Africn Am 144 mL/min/1.73 >59
BUN/Creatinine Ratio 11 8-19
Sodium, Serum 139 134-144
Potassium, Serum 3.8 3.5-5.2
Chloride, Serum 98 97-108
Carbon Dioxide, Total 23 20-32
Calcium, Serum 9.7 8.7-10.2
Protein, Total, Serum 7.5 6.0-8.5
Albumin, Serum 4.8 3.5-5.5
Globulin, Total 2.7 1.5-4.5
A/G Ratio 1.8 1.1-2.5
Bilirubin, Total 0.3 0.0-1.2
Alkaline Phosphatase, S 66 25-150
AST (SGOT) 15 0-40
ALT (SGPT) 10 0-55
Vitamin D, 25-Hydroxy 25.7L 30-100
TSH 1.57 .45-4.500
Vitamin B12 428 211-946
Folate (Folic Acid), Serum 18.0 >3.0

** These are from a couple weeks ago **
ANA Direct Negative
Creatine Kinase,Total,Serum 199 U/L 24-204
Calcitriol(1,25 di-OH Vit D) 46.8 pg/mL 10.0-75.0
(Note I take a multivitamin and 2,000 IU of vitamin D daily)
Lead, Blood (Adult) <1 ug/dL 0-19

LYME DISEASE CONFIRMATION TEST (86617) 3/27/2013 4:44 PM
Panel/Test Value Unit Normal Range
IgG P93 Ab. Absent
IgG P66 Ab. Absent
IgG P58 Ab. Absent
IgG P45 Ab. Absent
IgG P41 Ab. Absent
IgG P39 Ab. Absent
IgG P30 Ab. Absent
IgG P28 Ab. Absent
IgG P23 Ab. Absent
IgG P18 Ab. Absent
Lyme IgG WB Interp. Negative
Note: Positive: 5 of the following Borrelia-specific bands: 18,23,28,30,39,41,45,58, 66, and 93. Negative: No bands or banding patterns which do not meet positive criteria.
IgM P41 Ab. Absent
IgM P39 Ab. Absent
IgM P23 Ab. Absent
Lyme IgM WB Interp. Negative
RA Latex Turbid. 8.0 IU/mL 0.0-13.9
Panel/Test Value Unit Normal Range
Hep A Ab, IgM Negative Negative
HBsAg Screen Negative Negative
Hep B Core Ab, IgM Negative Negative
Hep C Virus Ab <0.1 s/co ratio 0.0-0.9
Uric Acid 5.8 mg/dL 3.5-7.2

I had more blood work taken this last week, I'll post it when they post my results. On the tests from the summer I wasn't taking anything. On the current tests I take a multivitamin, fish oil, some b12 type stuff that mrsD recommended, 2,000-4,000 iu of vitamin D a day, and SlowMag.

It can be pretty scary I know. I take fish oil with omega 3, a daily vitamin, and SlowMag 2 times a day. I think it was like 10 bucks at wal mart. I'm going to get my vitamin B and D checked this week and go from there on that. I think mine was caused mostly from alcohol, because my diet was awful when I drank all the time. Good luck to you and hopefully you'll find some relief.