Firstly, welcome and I am truly sorry you are going through this. We have some things in common, though! Sometimes that helps, just to know. I have family history of RA and scleroderma (CREST variant) on my mom's side. I started having sensory neuropathy at age 32 (now I am 43.) Mine was picked up on EMG, however, since it was long-fiber (the sural nerve.) I have tested negative for most autoimmune tests, the only exceptions were a mild-positive ANA and an B2 glycoprotein 1 (IgA) which is a marker for antiphospholipid antibodies in 2003 & 2005. I started Plaquenil in 2003 based on these tests, and I don't know if it helped me or hurt me (rare side effect of Plaquenil can be nerve damage.) I stopped taking it 6 weeks ago.

Long story short, my rheumy and my neurologist still think it is autoimmune based. Current labwork is all negative. It does seem to be progressing for me based on EMG results. It sucks to have something and not really know what is causing it.