O.O Tindamax...has a warning as causing Neuropathy....

http://www.drugs.com/disease-interac...,tindamax.html

Flagyl (the father of Tindamax and chemically related) can also cause lesions in the brain. This is dose and time dependent. I suspect Tindamax also will be implicated.

Thanks for that extra information on Lyme, as well.
It will be useful here. If you could stick around some and post to those you suspect have a Lyme component... that would be great.

Those stats are very alarming and concerning.

If you get hyper on the SAMe.. start more slowly at 1 every other morning on an empty stomach. I found this increased "energy" did wear off after about a month. I took SAMe for about 10 yrs (at 600mg aday mostly)...for my knee and arthritis. I healed my knee over a 3 yr period, and I avoided a knee replacement. I am much older than you, so the hyper thing did not last for me. But it was unmanageable for my son. He liked SAMe quite a bit but after a month, he got too irritable on it. He tried it 3 times and struck out each time.