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IllPn 02-23-2014 11:11 AM

Gerd
 
one more thing... Mrs D you mention taking antacids? Can that have an effect on any of this? I take rolaids and stopped taking my statins but think I will have to go back to them.
I am high risk for stroke as have migraines and with high cholesterol not much else I can do probably to lower mine. Sometimes it is just in the genes..
have you gone off all sugar and as to carbs you stay away from bread etc? What diet do you follow?

IllPn 02-23-2014 11:15 AM

oops
 
I see you put about taking Vitm D3 missed that some how

johnj7b7r6 02-23-2014 11:17 AM

Quote:

Originally Posted by mrsD (Post 1052938)
John, have you had a lung Xray recently? Some PN can come from hidden cancers...mostly of the lung in men. Mesothelioma is a risk factor for you if there are airborne particles coming into your office from workers, etc.

PN from cancer of this type is called paraneoplasia. Many other types of cancer can also cause this. There are markers in the blood that can be measured to see if this is present.

It is possible your PN is also coming from your back.

The B12 you take should be at least orally 1mg (1000mcg) and the methylcobalamin type. The cyano is not converted in some people who have the MTHFR methylation mutation. The D should be D3 and not D2...so check the label on your product.
It is suggested now to take the D separate from calcium and to not take more than 600mg a day of calcium when on a D supplement. (this is to avoid calcium depositing in the arteries).

I'm under medical surveillance as far as works goes (UK asbestos regulations) so no concerns there, mesothelioma generally has 20-40 year latency period and tends to present in typical cancer fashion of weight loss, pain on breathing etc.

It looks like I'm on D3 tablets so that's something.

My back is poor and I have no doubt that I am headed for the MRI scanner in a few weeks.

Stacy2012 02-23-2014 12:46 PM

My mother in law died of mesothelioma sarcomatoid cancer. She was exposed as a child/teen to asbestos from clothing her father wore when he came home from work and she did the laundry. Her symptoms were not "typical" as you mentioned and took a year to diagnose and by then she was bad off and died soon after.

I would be careful about the label of "typical symptoms" for that disease. I learned it can be anything but typical. Not suggesting you have it simply offering my experience. :)

IH8PN 02-23-2014 03:31 PM

Quote:

Originally Posted by johnj7b7r6 (Post 1052905)

My really troubling and depressing symptom is a dull/bruised foot pain pain, really typical of just having been standing too long. Quite literally I have pain by the time I have finished taking a shower in the morning - it starts within minutes of bearing weight. I can however walk/move continuously for a few hours before I just have to sit down and rest.

I can relate. I get a pretty intense ache in the soles of my feet if I stand in one place for more than a few minutes, however walking around isn't as bad. Some shoes make it worse for me like high arch supports really push into the arch of my foot causing pain to radiate up, although its really hard to pinpoint an exact location for the pain because it's just so vague and radiates. Sometimes the pain hurts more in the heel. Within a minute of sitting down the pain is usually gone, although I'll feel an occasional cramping soreness while lyng in bed. Just one of several symptoms that has popped up in the past few months and I have no idea the cause so as of now I can't be of much help.

johnj7b7r6 02-23-2014 04:16 PM

Quote:

Originally Posted by IH8PN (Post 1052997)
I can relate. I get a pretty intense ache in the soles of my feet if I stand in one place for more than a few minutes, however walking around isn't as bad. Some shoes make it worse for me like high arch supports really push into the arch of my foot causing pain to radiate up, although its really hard to pinpoint an exact location for the pain because it's just so vague and radiates. Sometimes the pain hurts more in the heel. Within a minute of sitting down the pain is usually gone, although I'll feel an occasional cramping soreness while lyng in bed. Just one of several symptoms that has popped up in the past few months and I have no idea the cause so as of now I can't be of much help.

That pretty much describes my experience, I tend to find the heels are worst though eventually the whole arch follows. Walking itself is fine unless it's a slow ambling kind of walk or one where I stop multiple times, as if browsing in shops for instance.

IH8PN 02-23-2014 10:15 PM

Quote:

Originally Posted by johnj7b7r6 (Post 1053000)
That pretty much describes my experience, I tend to find the heels are worst though eventually the whole arch follows. Walking itself is fine unless it's a slow ambling kind of walk or one where I stop multiple times, as if browsing in shops for instance.

Grocery shopping is usually bearable until I get to the checkout. Standing there waiting to pay gets excruciatingly painful!! I've done a lot of Googling in the past few weeks. I don't really come across very many stories with similar symptoms that aren't diagnosed with plantar fasciitis. Of all my pain and discomfort, it's really the only one that doesn't fit in as classical neuropathy signs. I have so many other classic symptoms that started around the same time that I find it hard to believe the aching feet isn't directly related.

St George 2013 02-24-2014 08:32 AM

Hello everyone :)
 
Anyone think it could be small fiber neuropathy ?

Just wanted to jump in here with that :)

Debi from Georgia

mrsD 02-24-2014 08:56 AM

Quote:

Originally Posted by IllPn (Post 1052943)
one more thing... Mrs D you mention taking antacids? Can that have an effect on any of this? I take rolaids and stopped taking my statins but think I will have to go back to them.
I am high risk for stroke as have migraines and with high cholesterol not much else I can do probably to lower mine. Sometimes it is just in the genes..
have you gone off all sugar and as to carbs you stay away from bread etc? What diet do you follow?

Acid reducing drugs like Prilosec (Proton Pump inhibitor) or H2 antagonists like Zantac etc, are more likely to prevent B12 absorption. Antacids would too if taken all the time everyday.

No, I do some carbs, but I have gone gluten free again a couple months ago for my GI issues. Seems to be working well. I tend to follow the Zone diet, which balances carbs, proteins, and good fats. 40% 30% 30%, respectively.

echoes long ago 02-24-2014 10:24 PM

I have had PN for almost 13 years now. My feet and lower legs got progressively number over that time and now have severe numbness. Even though they are deeply numb, i still get what i call broken bones feeling in my feet when i stand or walk. It literally feels like i am walking on broken bones. thefurther i walk the worse it gets, the more i stand the worse it gets, standing still in a line on a concrete floor is the worst. I also have chronic muscles fasiculations mostly in my calves. not all the time, but often. sometimes i just sit there and watch the muscles twitching as if they belonged to someone else. the cause of my pn is exposure to toxins. I was diagnosed with PN two years after my exposure via an EMG/NCS. I got my first symptoms within a month after the exposure. Honestly I thought it was a back problem, i ignored the growing numbness and pain until it became impossible. my PN is due to axonal damage.


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