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Old 03-01-2009, 03:10 AM #1
lexluger lexluger is offline
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Originally Posted by tag808 View Post
I wondered if anyone that has used poligrip has suffered severe digestive problems. I have used it for about 4 years and since that time have went from a size 9 to a size 1. My weight is currently 90lbs. Have been treated for IBS, Ulcertive Colitis and lactose intolerance, but so far nothing has helped. In the last year I have went from someone who could eat almost anything and really enjoyed food, to no appetite and unable to digest most food. I just recently explored if polygrip could be the culprit to find out about the Zinc. When I looked up the symptons of Zinc poisoning, the first thing listed was digestive problems, including diarreah which I now have up to 15 times a day. Any help on this would be appreciated
Tag
I have many of the same problems you described. I started having these symptoms about 2 or 3 years after I started using the cream. I developed kidney stones a few months after I started using the cream, and gall stones about 8 years later. I also went into a severe depression just afterward and have been struggling with it ever since (going on 7 years now.) I'm always weak and lethargic, and sometimes sleep way more than I should. The lethargy is so bad that I haven't been able to work at times. The stomach problems have also hindered my ability to live a normal life. I don't know if any or all of my problems could have been caused by the cream, but could it be possible?

I did some research and it seems that zinc overdose can cause a copper deficiency, and one of the symptoms of copper deficiency is chronic diarrhea. So that is a definite link. Google "copper deficiency" for more information.
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Old 03-01-2009, 08:07 AM #2
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Quote:
Originally Posted by lexluger View Post
I have many of the same problems you described. I started having these symptoms about 2 or 3 years after I started using the cream. I developed kidney stones a few months after I started using the cream, and gall stones about 8 years later. I also went into a severe depression just afterward and have been struggling with it ever since (going on 7 years now.) I'm always weak and lethargic, and sometimes sleep way more than I should. The lethargy is so bad that I haven't been able to work at times. The stomach problems have also hindered my ability to live a normal life. I don't know if any or all of my problems could have been caused by the cream, but could it be possible?

I did some research and it seems that zinc overdose can cause a copper deficiency, and one of the symptoms of copper deficiency is chronic diarrhea. So that is a definite link. Google "copper deficiency" for more information.
You should have a zinc/copper ratio done with a blood test.
One of the first signs of low copper is anemia.

More on copper:
http://lpi.oregonstate.edu/infocente...per/index.html

more on zinc:
http://lpi.oregonstate.edu/infocenter/minerals/zinc/

Zinc metabolism:
Quote:
Zinc Metabolism

The dietary intake of zinc is around 10-15 mg/day. It is present in meat and other protein foodstuffs, but intestinal absorption is affected by other dietary constituents. Absorbed zinc enters the liver where it is incorporated into zinc metalloenzymes and exported to peripheral tissue in plasma, bound to albumin. Of the total plasma zinc concentration of 12-25 µmol/l, over 90% is associated with albumin, <10% with alpha-2 macroglobulin, and a small amount, <1%, complexed to amino acids and other low molecular weight species.

Zinc homeostasis is achieved by regulation of enterohepatic re-circulation. An amount of zinc equivalent to the total absorbed zinc is re-excreted into the gut in intestinal fluids. In normal health zinc output by the gut is equal to the total dietary intake. Urinary excretion of zinc is low (around 10 µmol/day), and does not vary markedly with dietary supply. It is increased in catabolic states, by certain drugs and/or chelating agents.
from http://www.trace-elements.org.uk/zinc1.htm

This is a good monograph:
http://ods.od.nih.gov/FactSheets/Zinc.asp

Notice low zinc can also cause diarrhea.

Zinc is excreted in larger amounts in people who have pyroluria.
http://www.drkaslow.com/html/pyroluria.html
Many people have this disorder and don't know it. Today more
information is available on it. Don't expect your doctor to know this one.
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