Thank you,

I forgot to mention that B12 is normal (550) and D has recently been normal and I supplement daily.

I am not on a statin and don't have high cholesterol. I am in very good shape normally, running, hiking, and some weight lifting.

Given the acute onset my thoughts are also toward an immune-mediated response, whether a gammaglobinopathy, GBS variant, etc., but my neurology knowledge base is pretty well exhausted beyond those thoughts.

And thank you for the Quest link, I am studying it.

Have you figured it out or do you have any updates? thanks

you mention your ulnar I am assuming that is the nerve in the elbow I have constant spasms in my arm in that area both sides have some ulnar issues may not be any help to you but I am leaning on mine way too much so something to be aware of You Tube has some ulnar exercises as well mine has never become real painful...

You have received great input from one of the board' s biggest treasures (MrsD.) I had to reach out when I read concern about ALS. I'm a nurse and have a diagnosis of idiopathic sensimotor polyneuropathy. I have feared ALS from the onset of this five years ago. We medical people really are victims of having too much knowledge.

So, two things...I had widespread and fairly sudden onset of parasthesias much like yourself. I have been reassured by more than one neurologist specializing in MND that ALS doesn't present in this fashion, nor does it carry sensory malfunction with it. The sensory aspects more often than not take it out of the differential.

Secondly, diagnosing the cause as autoimmune in nature is usually not a straight path. Autoimmune diseases run through my mother's side of the family. My neurologist is convinced this is what my "idiopathic" cause will turn out to be. I've had negative ANA's all along. My blood has been rechecked about twice a year for five years. This recent check finally showed a glimmer of a cause: mildly positive neuronal ganglionic acetylcholine receptor antibodies.

I'm sorry you are dealing with this. It is especially frustrating to not know the cause.