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Old 10-19-2014, 08:46 AM #2
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janieg janieg is offline
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janieg janieg is offline
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Join Date: Jan 2014
Location: Maryland
Posts: 793
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I had 23andme testing done years ago. Even though they've been shut down by the FDA to reporting medical genetic results, you can still get tested and have access to your raw genetic data. Once you have the raw data, you can poke around in it and look at the results for specific genes.

If anyone here knows the SNPs (parts of genes) involved in SCN9A and SCN10A with regard to SFN or PN, I can check my 23andme data and see if those are SNPs they test. I remember trying to do this once, but only was able to find an article citing one SNP in SCN9A even though it said there were more.

23andme testing is $99 and is not something you do through a doctor.

I don't have much time now, but I'm going to try to compile a list in this post unless someone can come up with a comprehensive list. I'm by no means an expert on this, and am just Googling for relevant information.

I did just find an article that references four SNPs on SCN9A with regard to Small Fiber Neuropathy.

Gene: SCN9A
SNP: rs200945460, rs200398202, rs4369876, rs12478318
Reference: http://www.omim.org/entry/603415

Well, that's unfortunate. Of these four SNPs possibility associated with SFN, 23andme only reports on the last one, rs12478318.

I'm also just going to put this link here for future reference. These are the results of a "Small Fiber Neuropathy" serach on the NIH NCBI website that resulted in SFN-related gene hits.

https://www.ncbi.nlm.nih.gov/clinvar...=DetailsSearch

I'll work more on this later.

Last edited by janieg; 10-19-2014 at 09:27 AM.
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