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Old 12-08-2014, 10:30 AM #1
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I'm GG on rs6746030, and consider myself to have a pretty high tolerance of pain. (I have small fiber neuropathy.)

Did you happen to do a methylation analysis of your SNPs at this website?

http://geneticgenie.org/


Quote:
Originally Posted by ewr2san View Post
rs6746030 is an SNP in SCN9A that is linked to short fiber neuropathy, and the umbrella diagnosis of Fybromyalgia.

The board wont let me post the link to the studies

so you should google for a study titled "Pain perception is altered by a nucleotide polymorphism in SCN9A" head researcher Frank Reimann

and
"A SCN9A gene-encoded dorsal root ganglia sodium channel polymorphism associated with severe fibromyalgia" head researcher Gilberto Vargas-Alarcon

Im interested in others with rs6746030 AG who also suffer with pain syndromes like Fybromalgia. rs6746030 is tested by the 23andme test.
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Old 12-09-2014, 04:32 PM #2
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I have not done a methylation analysis with that site, but have used promethease for a lot of analysis beyond what 23andme provided. Ill give it a shot to see what it shows as well.
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Old 01-24-2015, 12:14 AM #3
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Quote:
Originally Posted by janieg View Post
I'm GG on rs6746030, and consider myself to have a pretty high tolerance of pain. (I have small fiber neuropathy.)

Did you happen to do a methylation analysis of your SNPs at this website?

http://geneticgenie.org/
I am AG on rs6746030 (I have small fiber neuropathy). I am sorting through 23 and me results with the genie.
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