Thank you for reply, and I wish you the best of luck with your PN. Glen mentioned the 'double crush' theory and that makes a lot of sense to me. Once the tissue/nerves are injured, they are just more susceptible to further insults even if original insult has been removed/rectified.
I think it's like having a bad back in a way, if you have a bad back seemingly innocent movements or temp changes can aggravate your condition and cause it to flare where 'normal people' feel nothing at all. It seems to be a management issue.

I believe the reason some people react to sugar negatively is a chemical pathway called the polyol pathway.

http://en.wikipedia.org/wiki/Polyol_pathway

Not all diabetics get this BTW... I recall a science article in the past saying only genetically prone people react to sugar this way.
About 30% of diabetics. Doctors and ads would have you think all diabetics are equal but they do differ.

Type II diabetes has an surplus of insulin also... and high insulin levels, interact with the Cox-2 pathway and favor it, at the expense of the Cox-1 path which is a maintenance path. The Cox-2 path is inflammatory, and inflammation causes pain.
This reaction may be blunted by fish oil. So people who react to sugar with more pain should be on fish oil at least for a while to see if that helps.

People with poor livers, damaged livers by virus infections or alcohol, are not going to make enough glycogen or glucose on a paleo diet. These people will always crave carbs, more than others. Carbs also favor synthesis of serotonin, and as such provide a form of calming, for many. High protein diets are well known for making some people anxious, irritable and hyper.

Thanks Mrs. D, so I think your comment is favouring some fish oil at least in my case. I already take a multi, Taurine, D, & 100 mg r-Lipoic acid & 2400 mg of Primrose oil, and a blend of vegetable amino acids for hair/skin,nails.
Is it ok to take the fish oil with the primrose oil? Also I was thinking of adding an herb called Gymnema. I found it on the Iherb website for sugar balance, since rlipoic acid actually worked for me for the first 2 weeks I was on it.

While not meeting the criteria for diabetes or even pre-diabetes, I am somewhere on the spectrum with "misbehaving" blood glucose levels. Carbs cause my bg to spike too high and stay too high, but not enough to cause a high A1c result.

I don't notice an increase in discomfort with my SFN when I overdo carbs, but I've still cut back drastically. A nice side effect has been easy weight loss.

Anyway, one thing I'm experimenting with right now is taking apple cider vinegar (organic, unfiltered, unpasteurized...like Bragg's) before I part in a carb laden meal. I need to do controlled comparison, but I've heard it can reduce your bg by significant amounts. I tried it before Christmas brunch which was loaded with sugar, and I couldn't believe how good my bg was 2 hours later. Like I said, though, I need to try a more controlled experiment with taking it and not taking it before carb consumption with the exact same amount of carbs.

Yes I read today that Apple cider is excellent for BLood sugar regulation.
Thank you for reply, and best of luck!!
Aussie

Try cutting back on the primrose. I am not a fan of high doses of this. Just do a little and see what happens. Fish oil or krill oil... will do some good I think. 2 or 3 regular fish oil or two regular Krill (or one super Krill concentrate).

Thanks Mrs D.,
I had a bottle of fishoil I was using as a door stopper of all things and started my fishoil today with half my primrose. I can't help wondering if this new anomaly is somehow also related to peri. Though I have no obvious symptoms I am 42 and have noticed some very mild changes.