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01-16-2015, 05:09 PM
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Just received preliminary results of my genetic screening. My methylation profile shows some mutations, actually a lot of them. Two homozygous, which are supposed to be more serious, and a lot of heterozygous. Can anyone help with analysing them? The information I received is a bit overwhelming, since it is all new to me. A quick, superficial read suggests I may have issues with vitamines D3, B12 and methylfolate.
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Multifocal motor neuropathy with conduction block since late 2005, diagnosed 12 November 2014 |
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01-16-2015, 09:46 PM
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Quote:
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| "Thanks for this!" says: | aneczka (01-17-2015), KnowNothingJon (01-17-2015) |
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01-17-2015, 04:20 AM
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Wisest Elder Ever
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So you will have to add methylfolate to your supplements
And raise your B12 to 5 mg a day at least.
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All truths are easy to understand once they are discovered; the point is to discover them.-- Galileo Galilei ************************************ . Weezie looking at petunias 8.25.2017 **************************** These forums are for mutual support and information sharing only. The forums are not a substitute for medical advice, diagnosis or treatment provided by a qualified health care provider. Always consult your doctor before trying anything you read here.
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| "Thanks for this!" says: | aneczka (01-17-2015) |
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01-17-2015, 08:53 AM
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Exactly, methylfolate was what I am thinking of.
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Multifocal motor neuropathy with conduction block since late 2005, diagnosed 12 November 2014 |
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01-17-2015, 08:57 AM
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Interestingly enough, it also shows a mutation which makes me vulnerable to celiac disease/ gluten sensitivity, and also some vitamine D absorption issues. I'll get them both tested.
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Multifocal motor neuropathy with conduction block since late 2005, diagnosed 12 November 2014 |
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01-17-2015, 09:08 AM
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Wisest Elder Ever
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Good thing you got the testing... now you can work around the mutations perhaps and regain some lost functions.
If you have Celiac and don't know it, you could be malabsorbing many other nutrients. So going gluten free may be a good idea, too.
__________________
All truths are easy to understand once they are discovered; the point is to discover them.-- Galileo Galilei ************************************ . Weezie looking at petunias 8.25.2017 **************************** These forums are for mutual support and information sharing only. The forums are not a substitute for medical advice, diagnosis or treatment provided by a qualified health care provider. Always consult your doctor before trying anything you read here.
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| "Thanks for this!" says: | aneczka (01-17-2015) |
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01-17-2015, 09:11 AM
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Been doing that already, but not very religiously. Now I have a reason to be systematic about it.
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Multifocal motor neuropathy with conduction block since late 2005, diagnosed 12 November 2014 |
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| "Thanks for this!" says: | mrsD (01-17-2015) |
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01-17-2015, 09:17 AM
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That spells no more eating out so much
 Which is not a good news, because cooking with two bad hands is a pain in the .. hands. Can anyone recommend a good cooking book for going gluten-free?
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Multifocal motor neuropathy with conduction block since late 2005, diagnosed 12 November 2014 |
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01-27-2015, 05:54 PM
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mrsD, how much methylfolate would you take for every, say, 1000 mg of methylcobalamin? Would you take it with food? Got it today, but not sure what dosage makes sense.
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Multifocal motor neuropathy with conduction block since late 2005, diagnosed 12 November 2014 |
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01-27-2015, 07:07 PM
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Wisest Elder Ever
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800mcg a day of the methylfolate to start. There are no food restrictions I know of for it.
The methylB12 requires empty stomach and no food after for about an hour. And this explains your gene in more detail: http://ghr.nlm.nih.gov/gene/SMN1
__________________
All truths are easy to understand once they are discovered; the point is to discover them.-- Galileo Galilei ************************************ . Weezie looking at petunias 8.25.2017 **************************** These forums are for mutual support and information sharing only. The forums are not a substitute for medical advice, diagnosis or treatment provided by a qualified health care provider. Always consult your doctor before trying anything you read here.
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| "Thanks for this!" says: | aneczka (01-28-2015) |
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