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Old 02-14-2015, 12:48 PM #1
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They did provide ranges which I failed to post here. The B6 reference range was 4.0–40.0 and my result was 110.4
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mrsD (02-14-2015)
Old 02-18-2015, 03:04 AM #2
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Default Test your B6 levels as you take !!!

If you are taking B6, I suggesting seriously testing and monitoring it.

My doctors gave me a big B6 overdose and made my neuropathy worse.

I have chemo induced PN. Doctors gave me B6 and other B vitamins. I bugged them later to test my values and found it was 11,000 !!! They actually made my neuropathy worse. It has since taken a year for my B6 levels to very slowly come back down and it still isn't near the normal range yet.

So, bug them to get periodically tested and over time you will see trends.

Do not take too much B6, or you may not help your situation.

Natalie
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Old 02-18-2015, 10:02 AM #3
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Question

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Originally Posted by v5118lKftfk View Post
If you are taking B6, I suggesting seriously testing and monitoring it.

My doctors gave me a big B6 overdose and made my neuropathy worse.

I have chemo induced PN. Doctors gave me B6 and other B vitamins. I bugged them later to test my values and found it was 11,000 !!! They actually made my neuropathy worse. It has since taken a year for my B6 levels to very slowly come back down and it still isn't near the normal range yet.

So, bug them to get periodically tested and over time you will see trends.

Do not take too much B6, or you may not help your situation.

Natalie
I tried to find the reference ranges, for B6 testing.
Here is one that goes into detail about lab procedures.
http://www.cdc.gov/nchs/data/nhanes/..._c_met_plp.pdf

This link says upper range to report is 200.

Similar to the B12 range only goes up to 2000 in the US...

I'd get that test repeated. Was it a "serum" report, or a red cell report. There are labs that do vitamin testing only from the cells, and not the serum. The ranges for that may be different.

If you had a plasma (serum) test run on a poorly handled sample where the red cells burst, that could give a factitious (falsely elevated), reading. This often happens with potassium testing.

How much B6 were you taking daily, and for how long?
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Old 02-26-2015, 08:33 PM #4
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Default b6 levels ??

My Dr wants to check my levels in a month. Maybe I should ask to go to different lab?
I was told to stop taking all vitamins. I'm continuing to take my vit. D, E, C, fish oil and biotin. I dont see how these would make it worse.
I have a ? If anyone knows. If your liver cant break down b6, does this mean your livers not working properly?
I read that b6 is water double, so how can u overdose w this vit.?
I did notice my urine was very yellow a couple hrs after Taking a High Potency Multi.
So I assumed my body was excreting the extra B vitamins.
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Old 02-27-2015, 09:30 AM #5
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Wink

Some B6 is stored in muscles for short periods of time to aid in metabolizing glycogen. It is stored as pyridoxal --the active form and not pyridoxine as is found in most vitamins.

The enzyme in the liver that converts pyridoxine to pyridoxal phosphate, is called pyridoxal kinase. It has been found to be blocked by some drugs. But not all drugs have been studied in this regard. Pyridoxal kinase uses as a cofactor the Vitamin B2 which is riboflavin. If this is low, then B6 cannot be activated properly.

And yes, typically the high dose B complexes are excreted quickly in the urine. The bright yellow is usually the B2 riboflavin showing up. If you take B6 alone, the urine would be lighter with a greenish tint. Excess B1 can give a yeasty odor to the urine or sweat.

I think taking the others you list would be ok, unless those are being tested also.
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Old 02-28-2015, 02:25 PM #6
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Default re: B6

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Originally Posted by mrsD View Post
Some B6 is stored in muscles for short periods of time to aid in metabolizing glycogen. It is stored as pyridoxal --the active form and not pyridoxine as is found in most vitamins.

The enzyme in the liver that converts pyridoxine to pyridoxal phosphate, is called pyridoxal kinase. It has been found to be blocked by some drugs. But not all drugs have been studied in this regard. Pyridoxal kinase uses as a cofactor the Vitamin B2 which is riboflavin. If this is low, then B6 cannot be activated properly.

And yes, typically the high dose B complexes are excreted quickly in the urine. The bright yellow is usually the B2 riboflavin showing up. If you take B6 alone, the urine would be lighter with a greenish tint. Excess B1 can give a yeasty odor to the urine or sweat.

I think taking the others you list would be ok, unless those are being tested also.
Thanks Mrs D for info. I dont fully grasp what your trying to say but anyway u mentioned
bf about there being 2 different lab tests for b6. Serum or blood cell would have different ranges. Is one of these tests more accurate than the other?
Thanks
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Old 02-28-2015, 03:07 PM #7
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Lightbulb

Mainstream doctors don't as a rule use the cell tests.

Some holistic ones do however. There is pyridoxal in red blood cells and if they burst during handling of the sample, that is reading serum levels, then a false elevated result occurs. This also happens for potassium. Doctors know this and reorder another test if potassium results are high. The medical term for this is a "factitious elevation".

I really don't put much stock in B6 testing. It is only really valuable for extreme lows.
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