I've only taken Amitriptyline but this worked well for me - not perfect but well. However it caused heart palpitations after three years so I had to stop. The neurologist said that most people with this issue with Amitriptyline would have the same problem with Nortriptylene too. I am slowly weaning off Cymbalta now having found that it didn't make enough difference to warrant the tummy issues (gnawing hunger constantly) and jaw clenching. I've only been taking it at 30/40mg for a few months now but am finding it hard to get off I must say so I would recommend you factor this in to your decision making. I'm down to halving capsules now but find I suffer quite a lot of dizziness, nausea and low mood each day as I move down doses.

However it has been the best tolerated of the three drugs I've tried to date for nerve pain and I have a couple of friends who swear by it and wouldn't let anyone take them off it for love nor money!