I have mixed axonal and demyelinating peripheral polyneuropathy. I have been tested for diabetes, B12, folate, thyroid and a whole slew of other things, all negative results. Therefore, it is diagnosed as idiopathic. I have been complaining of symptoms since 1996 but was told over and over that nothing was wrong. Just this year I saw a new neuro and after a battery of expensive tests I was diagnosed from an abnormal EMG-NCS. Was initially started on Neurontin 300mg, which was later increased to 600mg. Now we have added Cymbalta 30mg. Haven't noticed much of a difference, just sleepy. My symptoms (burning, tingling, weakness, hypersensitivity) come and go. Sometimes things will be good for several months and then for no apparent reason, BAM.....the symptoms are back. Does anyone else have the same experience where their symptoms come and go?