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05-14-2015, 08:40 PM | #1 | |||
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I'm not sure I understand your question. The low IgG is a primary immunodeficiency disease...a completely different medical condition from the neuropathy. I just happen to have both conditions and receive the IVIG for both. It replaces the IgG my body is unable to make on it's.
The dosing of IVIG for neuropathy is completely different and usually about 3 times more then required for an immune deficiency. So basically, if I understand your question, NO, the low IgG has nothing to do with the neuropathy and therefore not required to have a low IgG for it to work. The IVIG helps the low IgG (of an immune deficiency) by bringing the level up. The IVIG for neuropathy works as an immune modulator to help organize better immune function in autoimmune types of neuropathy. But the actual mechanics of how the IVIG helps neuropathy isn't completely understood yet...they just know it helps. Hope this helps. |
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"Thanks for this!" says: | Tunaboy (05-14-2015) |
05-14-2015, 08:47 PM | #2 | |||
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Quote:
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05-14-2015, 08:56 PM | #3 | |||
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IVIG is a big dose of IgG. Yet, when introducing it to the immune system with autoimmune activity it's seems to help modulate it and help it to function better. They really don't know why it works so well. This actually isn't uncommon for a medicine to work and they not know why. The use of Neurontin and other anti-seizure meds for neuropathic pain began as an accident of sorts. They just noticed that seizure patients receiving it start to have less pain. So they start using it for PN. They now know more about how it works but they didn't at the start.
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"Thanks for this!" says: | Tunaboy (05-15-2015) |
05-15-2015, 08:25 PM | #4 | |||
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If I ever get IVIG i sure hope it works. No other options really. And I got scared of prednisone after seeing a bunch of youtube vids about it. No thank you! My first neuro prescribed me 60mg daily! After doing my research I tossed the prescription out.
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05-16-2015, 06:52 PM | #5 | ||
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My IGG and IGM were both very high, and I was on IVIG. The IVIG was used to modulate the immune system in my case.
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05-17-2015, 12:56 AM | #6 | |||
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05-17-2015, 02:49 PM | #7 | ||
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With IVIG, plasmapherisis and rituxin it is believed the immune attack on my nerves was stopped.
I'm not 100% sure which one stopped it, or if it may have been the combination of them all. I did not "get better" or regain any lost nerves. I just stopped progressing, with the nerve damage staying in my lower legs/feet. |
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