Hi Aussie,

When I first started looking into it, I read somewhere that you can take 600 mg of ALA twice daily to help with neuropathy as long as you have no side effects, including your blood sugar going too low. I can't lay hands on the exact article I read now, but I do remember reading that. I started with 100 mg of R-LA, and when I felt no side effects, I bumped it up. I do believe it has helped me, but am soon going back down to 100 mg to see if I feel any difference. It is rather expensive.

I should also add that I tested low-normal for ALA in a NutrEval test, so that also factored into my decision.

I just did a little Googling and found this write-up on it. This wasn't what I read initially, but what I read was probably a summary of it as I remember it had references to a German study.

http://www.diabetesaction.org/site/P...lementary_5_12

"A small Romanian study of 26 patients found symptomatic improvement with oral ALA (600mg daily) after three months. Ziegler replicated these findings in the 2006 SYDNEY-2 trial, finding that oral doses of 600, 1200, or 1800mg of ALA for five weeks led to significant improvement in neuropathy symptoms, with the best safety profile at 600mg. Notably, side effects were observed and included nausea, vomiting, and vertigo, which increased in a dose-dependent manner between 1200 and 1800mg per day."

Cheers!

Janie