Think about getting the DNA testing for MTHFR errors.

Long term PNs could be due to this genetic mutation.

23andme.com does this online and also some others.
I don't know about Canadian medicine, but do ask if this is
available for your husband.

Using methylated supplements helps with those with MTHFR mutations.

Mrs D is 23andme doing genetic testing again?

Yes, they are...only limiting interpretation of results. You have to do that yourself.

They give the basic genetic info though.

Yes, I just recently had the testing done by 23and me. I costs about $100 US, and takes a few weeks to get the results back.

Once you have the results, you can go to the Genetic Genie website. It is free, and they will run a "Methylation Profile" and a "Detox Profile", to show you any mutations that affect your methylation cycle or impact your body's ability to detoxify itself. (I found I had a number of different things going on, and am currently working on adjusting supplements accordingly.)

I also ran my results through another website called Promethease. It does a more wide ranging analysis of many different health issues and costs $5. You need to really think about whether you want to do that though. In order to get all the info, 23andme makes you "consent" before they show your results on certain genes. (Like the one that shows I have a very high risk of developing alzheimers.) I sorta wish I hadn't looked at that one.

Hi Ragtop262

Because of my day job I have a reasonable understanding of AD.

"I have a very high risk of developing alzheimers."

If you would like to you could post the details of this genetic risk here (or by PM if you would prefer).

I would be happy to offer you thoughts about this.