Mrs. D, my husband (who definitely has no nerve damage) did the same thing as me...put a lot on one finger, covered it with a glove and waited. No wrinkling. I wonder if we're doing it wrong. I guess I'll try leaving it for 30 minutes uncovered today and see what happens. Also, we only each did one finger. I'll try a few more as you suggested in a pp. thanks

I believe the study found 80%+ correlation with the other tests for the diabetic neuropathy. Not 100%

You know, anyone can have reduced nerve functions.

thanks. just did it...had it on for 20 minutes and had to look under a bright light and have a tiny bit!. Put it on three fingers. Do you think leaving it on for 10 more minutes would make a big difference? I did have a negative skin punch so I at this point (since I have had this pain for so long) am thinking I do not have SFN even though I have all of the symptoms! Still waiting for my dr to come back from vacation though but it seems that the punch biospy is really the gold standard and I can't imagine getting a diagnosis with a negative one, although I'd loved to know why my feet burn and why my bladder is a MESS!!!

Would this test be for diabetic P/n or other types also?

I have never heard of this test. Very interesting. I had 2 punch biopsies, after my emg was negative, they can back positive. It took me over 2 years to get diagnosed. The EMG will be negative unless you have large fiber involvement. I am 35, otherwise healthy. Believe to be idiopathic. It’s now spreading up my legs. The weirdest thing is this new visual on the bottom of my feet. Anyone had these before? I attached a picture below. They are not brown or black like it may appear in the picture. They are bright orange and yellow. Happened over night and have been there for about a week now.

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Hi' I am not a pro on any of these issues I am still learning on my own P/N issues with lots of symptoms, Are you diabetic? do you think it might be circulation? Like I said I am not a pro you can put in google the colors of your feet and see what comes up. But just watch out as when ever I google anything on there site for any reason big or small most of the time for me anyway, they give the worst outcomes of the problem and scare the hell out of me. I wish I could help you but I bet someone here will answer your question as there are a lot of good people on this board, smart too....Dex.